Trisaccharide containing α2, 3-linked sialic acid is a receptor for mumps virus

M Kubota, K Takeuchi, S Watanabe… - Proceedings of the …, 2016 - National Acad Sciences
… Despite the availability of an effective vaccine, mumps virus (MuV) still causes outbreaks …
the trisaccharide containing an α2,3-linked sialic acid on the cell surface acts as a receptor for …

[HTML][HTML] The sialic acid binding activity of human parainfluenza virus 3 and mumps virus glycoproteins enhances the adherence of group B streptococci to HEp-2 cells

J Tong, Y Fu, F Meng, N Krüger… - Frontiers in Cellular …, 2018 - frontiersin.org
… to recognize the capsular sialic acid of GBS we demonstrate that GBS attaches in a sialic
acid-dependent way to transfected BHK cells expressing the HN protein of mumps virus (MuV) …

[HTML][HTML] Structural basis for Glycan-receptor binding by mumps virus hemagglutinin-neuraminidase

RE Forgione, C Di Carluccio, M Kubota, Y Manabe… - Scientific reports, 2020 - nature.com
… Interestingly, we found that the protein was able to bind the reducing sialic acid produced
during … by studying the interaction between free reducing sialic acid and the MuV-HN (Fig. S3). …

Identification of amino acids involved in the sialidase activity of the mumps virus hemagglutinin-neuraminadase protein

MN Waxham, J Aronowski - Virology, 1988 - Elsevier
… Released sialic acid was quantitated by the thiobarbituric acid assay. Hemagglutination
assays (HA) have been described (Server et a/., 1982) and were done using guinea pig red …

Molecular mechanism of the flexible glycan receptor recognition by mumps virus

M Kubota, R Matsuoka, T Suzuki, K Yonekura… - Journal of …, 2019 - Am Soc Microbiol
… an α2,3-linked sialic acid in the unbranched sugar chains … containing an α2,3-linked sialic
acid, such as 3′-sialyllactose (3′-… with the that of other sialic-acid using paramyxoviruses, an …

[HTML][HTML] … acid change 335 E to K affects the sialic-acid-binding and neuraminidase activities of Urabe AM9 mumps virus hemagglutinin–neuraminidase glycoprotein

J Reyes-Leyva, R Baños, M Borraz-Argüello… - Microbes and …, 2007 - Elsevier
… activity releases the sialic acid residues from viral progeny to … of virus particles by fusion of
the cell and viral membranes [1]. … of Urabe AM9 mumps virus differ in their sialic acid-binding …

[HTML][HTML] Roles of sialic acid, AXL, and MER receptor tyrosine kinases in mumps virus infection of mouse sertoli and leydig cells

F Wang, R Chen, Q Jiang, H Wu, M Gong… - Frontiers in …, 2020 - frontiersin.org
… Here, we describe that sialic acid, AXL, and MER receptor tyrosine kinases regulate MuV …
Sialic acid, AXL, and MER were present in Sertoli and Leydig cells. Sialic acid specifically …

[HTML][HTML] Unique tropism and entry mechanism of mumps virus

M Kubota, T Hashiguchi - Viruses, 2021 - mdpi.com
viruses preferentially recognizes α2,6-linked sialic acid, whereas that of avian influenza viruses
recognizes α2,3-linked sialic acid… of α2,6-linked sialic acids, whereas the avian intestinal …

The quantification of sialic acids released from guinea pig primary cell cultures for investigation of mumps virus entry and infection

A Štimac, M Lang Balija, D Forčić - Annual meeting of the Croatian …, 2021 - croris.hr
Mumps virus (MuV), an aerosol-transmitted human pathogen, … MuV- HN specifically
recognize sialic acid (SA) containing … primary cells to infection with different mumps virus strain. …

[HTML][HTML] On the potentials of sialic acid derivatives as inhibitors for the mumps virus: A molecular dynamics and quantum chemistry investigation

M Khavani, A Mehranfar, MRK Mofrad - Virus Research, 2023 - Elsevier
… and different compounds based on the α2-3-linked sialic acid… based on the sialic acid
against the mumps virus. Our results … sialic acids and their affinity to the mumps virus, which can …