New vessels, new approaches: angiogenesis as a therapeutic target in musculoskeletal disorders

SC Ballara, JM Miotla… - International journal of …, 1999 - Wiley Online Library
Musculoskeletal disorders such as rheumatoid arthritis (RA) and osteoarthritis are a
common cause of pain and disability. The vasculature is an important component of the …

[HTML][HTML] Mesenchymal stem cells as therapeutic target of biophysical stimulation for the treatment of musculoskeletal disorders

M Viganò, V Sansone, MC d'Agostino, P Romeo… - Journal of orthopaedic …, 2016 - Springer
… In summary, MSC-based therapiesmusculoskeletal disorders. The advances discussed
in this review highlight the progress being made toward clinical translation of such therapeutic

[HTML][HTML] Recent trends in pharmacological treatment of musculoskeletal disorders

Z Zong, L Xu, N Zhang, WH Cheung, G Li… - Frontiers in …, 2022 - frontiersin.org
… Thanks to the development of the high-throughput genomics technologies, potential therapeutic
targets of OA can now be identified by bioinformatic screening, and such technology can …

[HTML][HTML] Substance P, a promising therapeutic target in musculoskeletal disorders

KR Ko, H Lee, SH Han, W Ahn, DK Kim, IS Kim… - International Journal of …, 2022 - mdpi.com
… SP-NK1R pathway in the pathogenesis of musculoskeletal disorders and the evidence for
its role as a therapeutic target for these disorders, which are major public health problems in …

[PDF][PDF] Musculoskeletal: Where are we with treating musculoskeletal disorders?

IR Orriss, VE MacRae - Current Opinion in Pharmacology, 2016 - core.ac.uk
… on the causes of and therapeutic options available to treat … novel therapeutic targets in
the future, are also reviewed. … within the musculoskeletal field with several therapies being …

Theranostic agents in musculoskeletal disorders

S Katal, A Maldonado, J Carrascoso, M Assadi… - PET clinics, 2021 - pet.theclinics.com
… have shown potential for targeted imaging and therapy in a variety of musculoskeletal
illnesses. … Endosialin protein expression and therapeutic target potential in human solid tumors: …

Signal transduction pathway through activin receptors as a therapeutic target of musculoskeletal diseases and cancer

K Tsuchida, M Nakatani, A Uezumi, T Murakami… - Endocrine …, 2008 - jstage.jst.go.jp
… In this review, we discuss the role of signaling through activin receptors as therapeutic
targets of intractable neuromuscular diseases, endocrine disorders and cancers. …

[HTML][HTML] Therapy for musculoskeletal disorders

JA Gasser - Journal of orthopaedic translation, 2016 - ncbi.nlm.nih.gov
… that is perhaps the most promising emerging therapeutic target for the treatment of
osteoporosis and osteoporotic fracture. At present, osteoanabolic therapy is limited to the use of …

[HTML][HTML] Potential therapeutic targets of macrophages in inhibiting immune damage and fibrotic processes in musculoskeletal diseases

J Zhu, J Fan, Y Xia, H Wang, Y Li, Z Feng… - Frontiers in …, 2023 - frontiersin.org
… tissue damage in skeletal muscle disorders, as well as fibrosis … therapeutic targets for
treating musculoskeletal disorders (3–… and recovery of various musculoskeletal disorders (9). …

[HTML][HTML] Oligonucleotide therapeutics for age-related musculoskeletal disorders: Successes and challenges

TA Nicholson, M Sagmeister, SN Wijesinghe, H Farah… - Pharmaceutics, 2023 - mdpi.com
… Since MMPs have also been implicated in non-cancer driven osteoporosis [95,96], development
of similar oligonucleotide therapies targeting other MMPs may also be effective in such …