… mutation analysis. We present the first reported case of meningioma in a patient with Werner
syndrome and a confirmed major mutation. … meningioma associated with Werner syndrome. …

… Gray lines indicate frameshift mutations causing deletion of exon(s). D, Predicted proteins. …
produced from mutations in the WRN gene. Mutation Analysis Mutations were detected by …

… Samples were collected from individuals with Werner syndrome participating in our International
Registry of Werner Syndrome (www.wernersyndrome.org), supplemented by materials …

… and they described four mutations, designated mutations 1–4… population analyzed here, we
previously observed mutations … Toward localization of the Werner syndrome gene by linkage …

… the pheno typic expression of Werner syndrome features in homozy gotes … mutations in the
protein, we characterized the mutations in the WRN gene in a Caucasian family with Werner …

… Werner syndrome (WS), also known as adult progeroid syndrome, is an autosomal-… In
this analysis, the clinical signs and symptoms listed in the diagnostic criteria were compared. …

… syndromes. One prominent example is our work to better define patients with “atypical Werner
syndrome (… , but were found on subsequent analysis to lack WRN mutations. As of 2015, …

… mutation, which was recently identified in a WS patient. Our biochemical experiments with
purified mutant recombinant WRN protein showed that the G574R mutation … Werner syndrome …

… Mutation and haplotype analyses of the Werner’s syndrome gene based on its genomic
structure: genetic epidemiology in the Japanese population. Hum Genet. 1997;100(1):123– 130. …

… mutations was studied in 89 Japanese Werner’s syndrome (WRN) patients by examining the
previously described mutations 1– 4 as well as a new mutation … the Werner syndrome gene …