The role of mutation bias in adaptive evolution
EI Svensson, D Berger - Trends in ecology & evolution, 2019 - cell.com
… mutation bias in adaptive evolution. We find little support for mutation bias as an independent
force in adaptive evolution… entirely consistent with standard evolutionary theory. We further …
force in adaptive evolution… entirely consistent with standard evolutionary theory. We further …
[HTML][HTML] Mutation bias interacts with composition bias to influence adaptive evolution
… evolution of genetic diversity, mutational robustness, and evolvability. Taken together, our
… show that mutation bias and composition bias interact to influence adaptive evolution under …
… show that mutation bias and composition bias interact to influence adaptive evolution under …
Mutation bias shapes the spectrum of adaptive substitutions
… S4, even under the assumption that 40% of the events are contaminants, we observe a
strong and statistically significant influence of mutation bias on adaptive evolution. In fact, we …
strong and statistically significant influence of mutation bias on adaptive evolution. In fact, we …
Mutation bias and the predictability of evolution
AV Cano, BL Gitschlag… - … of the Royal …, 2023 - royalsocietypublishing.org
… mutation bias is anticipated to improve evolutionary forecasting, in regard to topics such as
infectious diseases, cancer and other kinds of somatic evolution… underlying adaptive evolution…
infectious diseases, cancer and other kinds of somatic evolution… underlying adaptive evolution…
The role of mutation bias in adaptive molecular evolution: insights from convergent changes in protein function
… Mutation bias is known to exert an important influence on patterns of neutral molecular evolution
[7], but our understanding of mutation … orienting factor in adaptive evolution as well [8,9]. …
[7], but our understanding of mutation … orienting factor in adaptive evolution as well [8,9]. …
Male‐biased mutation, sex linkage, and the rate of adaptive evolution
M Kirkpatrick, DW Hall - Evolution, 2004 - academic.oup.com
… influence rates of neutral molecular evolution (Miyata et al… adaptive evolution when mutations
favored by positive selection are limiting. We might anticipate that the most rapidly evolving …
favored by positive selection are limiting. We might anticipate that the most rapidly evolving …
Genomic mutation rates that neutralize adaptive evolution and natural selection
PJ Gerrish, A Colato… - Journal of The Royal …, 2013 - royalsocietypublishing.org
… occurs among genotypes or classes as a diffusion process that is strongly biased in favour
of deleterious mutations. Mathematical formulations of this model are given in appendix A. …
of deleterious mutations. Mathematical formulations of this model are given in appendix A. …
Population genetics, pleiotropy, and the preferential fixation of mutations during adaptive evolution
MA Streisfeld, MD Rausher - Evolution, 2011 - academic.oup.com
… Given the potential for a strong mutation bias against TF mutations causing … that evolutionary
transitions in floral hue preferentially will fix CIS(P) mutations instead of COD(P) mutations. …
transitions in floral hue preferentially will fix CIS(P) mutations instead of COD(P) mutations. …
The genomic rate of adaptive evolution
A Eyre-Walker - Trends in ecology & evolution, 2006 - cell.com
… that have been fixed by adaptive evolution, a statistic I refer to … of estimating the level of
adaptive evolution, it is generally … -synonymous mutations, because these can bias the estimate …
adaptive evolution, it is generally … -synonymous mutations, because these can bias the estimate …
Adaptive evolution: evaluating empirical support for theoretical predictions
CF Olson-Manning, MR Wagner… - Nature Reviews …, 2012 - nature.com
… Moving beyond the theory of adaptive evolution, we discuss how adaptations can arise, … ;
other evolutionary forces include genetic drift, mutation, migration and biased gene conversion …
other evolutionary forces include genetic drift, mutation, migration and biased gene conversion …
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