The role of mutation bias in adaptive evolution

EI Svensson, D Berger - Trends in ecology & evolution, 2019 - cell.com
mutation bias in adaptive evolution. We find little support for mutation bias as an independent
force in adaptive evolution… entirely consistent with standard evolutionary theory. We further …

[HTML][HTML] Mutation bias interacts with composition bias to influence adaptive evolution

AV Cano, JL Payne - PLoS computational biology, 2020 - journals.plos.org
evolution of genetic diversity, mutational robustness, and evolvability. Taken together, our
… show that mutation bias and composition bias interact to influence adaptive evolution under …

Mutation bias shapes the spectrum of adaptive substitutions

AV Cano, H Rozhoňová, A Stoltzfus… - Proceedings of the …, 2022 - National Acad Sciences
… S4, even under the assumption that 40% of the events are contaminants, we observe a
strong and statistically significant influence of mutation bias on adaptive evolution. In fact, we …

Mutation bias and the predictability of evolution

AV Cano, BL Gitschlag… - … of the Royal …, 2023 - royalsocietypublishing.org
mutation bias is anticipated to improve evolutionary forecasting, in regard to topics such as
infectious diseases, cancer and other kinds of somatic evolution… underlying adaptive evolution

The role of mutation bias in adaptive molecular evolution: insights from convergent changes in protein function

JF Storz, C Natarajan, AV Signore… - … of the Royal …, 2019 - royalsocietypublishing.org
Mutation bias is known to exert an important influence on patterns of neutral molecular evolution
[7], but our understanding of mutation … orienting factor in adaptive evolution as well [8,9]. …

Male‐biased mutation, sex linkage, and the rate of adaptive evolution

M Kirkpatrick, DW Hall - Evolution, 2004 - academic.oup.com
… influence rates of neutral molecular evolution (Miyata et al… adaptive evolution when mutations
favored by positive selection are limiting. We might anticipate that the most rapidly evolving

Genomic mutation rates that neutralize adaptive evolution and natural selection

PJ Gerrish, A Colato… - Journal of The Royal …, 2013 - royalsocietypublishing.org
… occurs among genotypes or classes as a diffusion process that is strongly biased in favour
of deleterious mutations. Mathematical formulations of this model are given in appendix A. …

Population genetics, pleiotropy, and the preferential fixation of mutations during adaptive evolution

MA Streisfeld, MD Rausher - Evolution, 2011 - academic.oup.com
… Given the potential for a strong mutation bias against TF mutations causing … that evolutionary
transitions in floral hue preferentially will fix CIS(P) mutations instead of COD(P) mutations. …

The genomic rate of adaptive evolution

A Eyre-Walker - Trends in ecology & evolution, 2006 - cell.com
… that have been fixed by adaptive evolution, a statistic I refer to … of estimating the level of
adaptive evolution, it is generally … -synonymous mutations, because these can bias the estimate …

Adaptive evolution: evaluating empirical support for theoretical predictions

CF Olson-Manning, MR Wagner… - Nature Reviews …, 2012 - nature.com
… Moving beyond the theory of adaptive evolution, we discuss how adaptations can arise, … ;
other evolutionary forces include genetic drift, mutation, migration and biased gene conversion …