… mutation carrier, were between 25 and 80-years-old, and had no prior history of cancer, other
than breast cancer… Subjects who had been diagnosed with unilateral breast cancer prior to …

… a prior diagnosis of breast cancer, the risk reduction in BRCA1 mutation carriers was a HR
… a lower breast cancer risk in BRCA2 mutation carriers than in BRCA1 mutation carriers (64% …

… /2 mutation carriers reduces the risk of a second breast cancer … risk in patients with moderate
penetrance gene mutations, … benefits of contralateral surgical risk reduction should include …

… factors from the family history due to being a BRCA1/2 mutation carrier … against breast
cancer was ascertained among carriers of BRCA1, but no similar significant reduction was …

… the numbers of BRCA2 mutation carriers, and especially the … a reduced BC risk after RRSO
for BRCA1/2 mutation carriers … BC risk reduction after RRSO in BRCA1/2 mutation carriers. …

… to study the efficacy of BRRM on BC risk reduction in healthy BRCA1/2 mutation carriers.
However, the ultimate goal of risk-reducing mastectomy is to improve survival, eventually being …

… whether the breast cancer risk reduction conferred by BPO in BRCA1/2 mutation carriers is
… with BRCA1/2 mutations will reduce their risk of breast cancer through BPO irrespective of …

… /2 mutation carriers undergo PO at a mean age of 45, 7 we assumed that reported breast
cancer incidence 2 … We assumed that the breast cancer risk reduction after premenopausal …

… mutation carriers with respect to risk reduction and mortality. Primary studies of BRCA mutation
carriers … review demonstrate a significant risk reduction in breast cancer incidence. The …

… Low uptake and interest in tamoxifen/raloxifene for breast cancer risk reduction seen in
our study is a consistent observation across studies and regions [28, 48]. Women have …