Mutation rate in human microsatellites: influence of the structure and length of the tandem repeat

B Brinkmann, M Klintschar, F Neuhuber… - The American Journal of …, 1998 - cell.com
repeats and the mutation rate was observed. Our data demonstrate that mutation rates of …
orders of magnitude and that different alleles at one locus exhibit different mutation rates. …

A brief review of short tandem repeat mutation

H Fan, JY Chu - Genomics, Proteomics and Bioinformatics, 2007 - academic.oup.com
… Short tandem repeats (STRs) are short tandemly repeated DNA sequences that involve a
repetitive unit of 1–6 bp. Because of their polymorphisms and high mutation rates, STRs are …

Mutation of human short tandem repeats

JL Weber, C Wong - Human molecular genetics, 1993 - academic.oup.com
… Observed mutation rates for individual STRPs ranged from 0 to 8x10~3 . The average
mutation rate for tetranucleotide STRPs was nearly four times higher than the average rate for …

Mutation rates at Y chromosome short tandem repeats in Texas populations

J Ge, B Budowle, XG Aranda, JV Planz… - Forensic Science …, 2009 - Elsevier
… of no correlation between the mutation rate and repeat number is 0.030. The highest
mutation rate of alleles was found at the DYS389II marker with one mutation in 22 alleles of “33”, …

Tandem-Repeat Patterns and Mutation Rates in Microsatellites of the Nematode Model Organism Pristionchus pacificus

RI Molnar, H Witte, I Dinkelacker… - G3: Genes …, 2012 - academic.oup.com
… We have analyzed the tandem repeat pattern of the P. pacificus genome and studied the …
mutation rates for microsatellite markers. From the mutation patterns and mutation rates

The effective mutation rate at Y chromosome short tandem repeats, with application to human population-divergence time

LA Zhivotovsky, PA Underhill, C Cinnioğlu… - The American Journal of …, 2004 - cell.com
… We estimate an effective mutation rate at an average Y chromosome short-tandem repeat
locus as 6.9×10 −4 per 25 years, with a standard deviation across loci of 5.7×10 −4 , using …

Mutation and selection processes regulating short tandem repeats give rise to genetic and phenotypic diversity across species

M Verbiest, M Maksimov, Y Jin… - Journal of …, 2023 - academic.oup.com
repeats or those with long repeat units (>4bp), have low mutation rates and may not be
polymorphic in a population. (b) Repeats with rapid mutation rates may show a wide range of …

Interpreting short tandem repeat variations in humans using mutational constraint

M Gymrek, T Willems, D Reich, Y Erlich - Nature genetics, 2017 - nature.com
… The key insight of our mutation rate estimation procedure is that different classes of … undefined
standard errors with mutation rates likely below our mutation rate detection threshold (cyan…

Replication slippage versus point mutation rates in short tandem repeats of the human genome

D Pumpernik, B Oblak, B Borštnik - Molecular Genetics and Genomics, 2008 - Springer
… ) exhibit mutation rates from 10 −4 to 10 −3 mutations per locus … of 100 bp—these mutation
rates would correspond to two orders … We report the mutabilities of short tandem repeats as a …

[PDF][PDF] Mutation rates at 23 different short tandem repeat loci

EM Dauber, W Bär, M Klintschar, F Neuhuber… - International Congress …, 2003 - isfg.org
… The mutation rates of microsatellites observed in this study … to two complete repeat units and
more mutations in the male … higher mutation rates of loci with longer uninterrupted repeats, …