Natural polymorphisms and unusual mutations in HIV-1 protease with potential antiretroviral resistance: a bioinformatic analysis

C Mata-Munguía, M Escoto-Delgadillo… - BMC …, 2014 - Springer
mutations to protease inhibitors (PIs). Emerging mutations in human immunodeficiency virus
type 1 (HIV-1) … between natural HIV-1 polymorphisms and unusual HIV-1 mutations that …

Mutations and polymorphisms associated with antiretroviral drugs in HIV-1C-infected African patients

F Doualla-Bell, S Gaseitsiwe… - Antiviral Chemistry …, 2004 - journals.sagepub.com
HIV-1 RT and PR mutations and polymorphisms Phylogenetic analysis revealed that all 22
sequences in this study clustered within the HIV-1C … for human immunodeficiency virus type 1-…

[HTML][HTML] HIV-1 drug resistance mutations: an updated framework for the second decade of HAART

RW Shafer, JM Schapiro - AIDS reviews, 2008 - ncbi.nlm.nih.gov
… are associated with nonnucleoside reverse transcriptase inhibitor resistance including
major primary and secondary mutations, non-polymorphic minor mutations, and …

HIV1 genetic variability and clinical implications

MM Santoro, CF Perno - International Scholarly Research …, 2013 - Wiley Online Library
… the presence of some polymorphisms that can influence both the emergence of drug-…
mutations and the response to drugs. For example, polymorphisms at residues 20 and 36 of HIV-1

Human genetic polymorphisms affecting HIV-1 diseases

T Shioda, EE Nakayama - International journal of hematology, 2006 - Springer
… with a CCR5 promoter mutation. Nat Med. 1998;4:350-353. … –589T polymorphism on human
immunodeficiency virus type 1 disease … A point mutation in CD45 may be associated with an …

Effect of sequence polymorphism and drug resistance on two HIV1 Gag processing sites

A Feher, IT Weber, P Bagossi, P Boross… - European journal of …, 2002 - Wiley Online Library
HIV-1 proteinases Oligopeptides including both natural sequence polymorphisms and
resistant mutations of the NC/p1 cleavage site sequences were assayed as substrates of HIV-1

Amplification of the effects of drug resistance mutations by background polymorphisms in HIV-1 protease from African subtypes

A Velazquez-Campoy, S Vega, E Freire - Biochemistry, 2002 - ACS Publications
mutations and evaluate any differences with the B subtype, we decided to incorporate the
V82F/I84V mutation within the framework of the three different HIV-1 … -resistant mutations of the …

HIV-1 diversity versus HLA class I polymorphism

HAF Stephens - Trends in immunology, 2005 - cell.com
HIV-1 is rapidly diversifying in African, Asian and Caucasoid populations, which in parallel
display extensive polymorphism … are imprinting mutations in HIV-1, which in turn affects HIV-1

Polymorphism of HIV type 1 gag p7/p1 and p1/p6 cleavage sites: clinical significance and implications for resistance to protease inhibitors

F Bally, R Martinez, S Peters, P Sudre… - AIDS research and …, 2000 - liebertpub.com
… of cleavage site mutations. The aim of this study is to explore (1) the polymorphism of the p7/p1
… D: Second locus involved in human immunodeficiency virus type 1 resistance to protease …

Distinct resistance mutation and polymorphism acquisition in HIV-1 protease of subtypes B and F1 from children and adult patients under virological failure

AT Dumans, CC Barreto, AF Santos, M Arruda… - Infection, Genetics and …, 2009 - Elsevier
… to compare the differences between human immunodeficiency virus type 1 (HIV-1) of B and
… (PI)-associated resistance mutations and of other polymorphisms at the protease (PR) gene, …