… Mycobacterium tuberculosis (Mtb) and the host leads to a complex and multifaceted immune
response … , are traditionally considered the pillars of immune defense against Mtb and their …

… understanding of Mycobacterium tuberculosis survival in macrophages, the interaction of M.
… paradigm that innate immune response generated in the host in response to Mtb infection is …

… The first step in initiating an immune response to Mycobacterium tuberculosis is detection …
), have been proposed to contribute to recognition of M. tuberculosis ( Figure 1 ). Studies of …

… There are 9 million cases of active tuberculosis reported annually; however, an estimated
one-third of the world's population is infected with Mycobacterium tuberculosis and remains …

… We know Mycobacterium tuberculosis (Mtb) is inhaled… mycobacterial antigens enable
antigen-presenting cells (APCs) to activate T lymphocytes as critical mediators of acquired immune …

… Cell-mediated immunity is necessary for protection, and healthy tuberculin-positive … mediated
immune response in healthy tuberculin-positive individuals to those of tuberculosis patients …

… The initial interaction of Mycobacterium tuberculosis with phagocytes through Toll-like
receptors can affect induction of the adaptive response by inflammatory cytokine production, as …

… Mycobacterium tuberculosis is one of the most ubiquitous pathogens in the world: estimates
are that roughly one third of the world's population is infected with the bacillus, and it is …

… intri‐cacies of the human immune response to MTB infection and to explore possible
differences in the genetic regulation of the host immune responses in various human populations. …

… -TB gold-in-tube and T-SPOT TB test, like the TST, measures a cellular immune response
to recent or remote M. tuberculosis exposure and is a marker of immune sensitization by M. …