T-cell-mediated protection of mice against virulent Mycobacterium tuberculosis
… We sought to protect CBA mice against tuberculosis using in vivo transfer of a T-cell line …
vitro with Mycobacterium tuberculosis. This line induces total bacteriostasis in vitro. In mice that …
vitro with Mycobacterium tuberculosis. This line induces total bacteriostasis in vitro. In mice that …
Enhanced protection to Mycobacterium tuberculosis infection in IL‐10‐deficient mice is accompanied by early and enhanced Th1 responses in the lung
PS Redford, A Boonstra, S Read, J Pitt… - European journal of …, 2010 - Wiley Online Library
… show here that Mycobacterium tuberculosis (Mtb) infection in the absence of IL-10 (IL-10 −/−
mice) … of Mtb-infected mice. This suggests that IL-17 may contribute to dissemination of Mtb. …
mice) … of Mtb-infected mice. This suggests that IL-17 may contribute to dissemination of Mtb. …
The live Mycobacterium tuberculosis phoP mutant strain is more attenuated than BCG and confers protective immunity against tuberculosis in mice and guinea pigs
C Martin, A Williams, R Hernandez-Pando, PJ Cardona… - Vaccine, 2006 - Elsevier
… Both protein and DNA vaccines induce partial protection against experimental tuberculosis
infection in mice, however, their efficacy has generally been equivalent to or less than that …
infection in mice, however, their efficacy has generally been equivalent to or less than that …
Mycobacterium tuberculosis‐activated dendritic cells induce protective immunityin mice
RE Tascon, CS Soares, S Ragno, E Stavropoulos… - …, 2000 - Wiley Online Library
… Recently, BCG-infected DC were shown to protect mice against an aerosol challenge with
M. tuberculosis; 16 however, in these experiments the DC were given intratracheally a route …
M. tuberculosis; 16 however, in these experiments the DC were given intratracheally a route …
Tumor necrosis factor-α is required in the protective immune response against Mycobacterium tuberculosis in mice
JAL Flynn, MM Goldstein, J Chan, KJ Triebold, K Pfeffer… - Immunity, 1995 - cell.com
… are essential for protection against tuberculosis in mice, and for … mice, but necrosis was
observed only in mice deficient in … necessary conditions for protection against murine M. fuberculo…
observed only in mice deficient in … necessary conditions for protection against murine M. fuberculo…
Mycobacterium tuberculosis arabinomannan–protein conjugates protect against tuberculosis
B Hamasur, M Haile, A Pawlowski, U Schröder… - Vaccine, 2003 - Elsevier
… subcutaneous immunization with the AMOs–antigen 85B conjugate in alum provided
significant protection compared to sham (alum only) immunized mice (P<0.021) as estimated by …
significant protection compared to sham (alum only) immunized mice (P<0.021) as estimated by …
Mycobacterium tuberculosis ΔRD1 ΔpanCD: a safe and limited replicating mutant strain that protects immunocompetent and immunocompromised mice against …
…, T Hsu, B Chen, MH Larsen, KV Jalapathy, M Chen… - Vaccine, 2006 - Elsevier
… mouse model showed that the anti-tuberculosis protection … protection seen after immunization
of CD4 −/− mice with the … 2 6030-induced protection of CD4 −/− mice against a tuberculous …
of CD4 −/− mice with the … 2 6030-induced protection of CD4 −/− mice against a tuberculous …
Effective vaccination of mice against Mycobacterium tuberculosis infection with a soluble mixture of secreted mycobacterial proteins
P Andersen - Infection and immunity, 1994 - Am Soc Microbiol
… tuberculosis cells release protective antigens during growth. … Human tuberculosis caused
by Mycobacterium tuberculosis re… In the second series of protection experiments, the mice …
by Mycobacterium tuberculosis re… In the second series of protection experiments, the mice …
Protection of mice from Mycobacterium tuberculosis by ID87/GLA-SE, a novel tuberculosis subunit vaccine candidate
HP Windish, MS Duthie, G Ireton, E Lucas… - Vaccine, 2011 - Elsevier
… -SE immunization reduces Mycobacterium tuberculosis bacterial burden in C57BL/6 mice. …
Two million people die from Mycobacterium tuberculosis (Mtb) infection each year and it is …
Two million people die from Mycobacterium tuberculosis (Mtb) infection each year and it is …
A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis
VK Sambandamurthy, X Wang, B Chen, RG Russell… - Nature medicine, 2002 - nature.com
… of Mycobacterium tuberculosis, newer control strategies in the form of a better vaccine could
decrease the global incidence of tuberculosis… conferred protection in C57BL/6J mice against …
decrease the global incidence of tuberculosis… conferred protection in C57BL/6J mice against …
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