… Mycobacterium tuberculosis. The present status of the attempts to characterize the protective
immune … characterization of target molecules recognized by protective cells. This paper will …

… immune infiltrate [3]. A contrasting school of thought ascribes active disease progression to
MTB-mediated dysregulation of the immune … the host’s protective immune response during …

… is not necessarily part of the mechanism of protection. In fact, a new vaccine may induce
protective immunity without engaging the pathways constituting “natural” protection. Second, …

… for mounting a protective immune response against M. tuberculosis remains controversial. …
We propose that IL-18 plays a more critical role in promoting protective immunity against TB …

… fewkey molecules of M. tuberculosis that are capable of inducing protective immunity, could
… rium, it might induce a stronger protective immune response than a whole-bacterium vaccine…

… Examination of the bacterial stress reporter strain hspX’::GFP, smyc’::mCherry Erdman
Mycobacterium tuberculosis at the level of different host phagocyte populations in murine lung …

… As Mtb is an intracellular bacterium, protective immunity is … Mycobacterium tuberculosis
infection may already induce … the current knowledge of protective immune responses in TB …

… Disease as an eventual but not a necessary consequence of infection results from a sensitive
balance between protective immunity and destructive pathology. Early events, governed …

… ined protective immunity in IL-15–deficient mice after infection with Mycobacterium bovis …
development of long-lasting protective immunity to mycobacterial infection via sustaining CD8+ …

… a wide array of immune responses in the infected host. It is now clear that both CD4 and
CD6 T cells contribute to the protective immune response to M. tuberculosis (Orme and Collins, …