… targets and mechanisms of action have not been elucidated. In this study, we investigated
the effects of pirfenidone on proliferation, TGF-β-induced differentiation and fibrogenic activity …

… effects of pirfenidone on cardiac fibroblast behavior have not been examined. In this study,
we investigated whether pirfenidone … as proliferation, myofibroblast differentiation, migration …

… TGF-β1 induced differentiation of orbital fibroblasts into myofibroblasts, which dominated …
we observed that pirfenidone reduced TGF-β1-mediated myofibroblast differentiation and ECM …

… Mitophagy has been implicated in myofibroblast differentiation … In this study, the effect of
PFD on autophagy/mitophagy … of myofibroblast differentiation during insufficient mitophagy. …

… TGF-β1-induced differentiation of NHLFs and IPF fibroblasts into myofibroblasts. Levels of
α-SMA, a marker of fibroblast to myofibroblast differentiation, were determined in NHLFs and …

… effect of PFD treatment on FMT in pHLFs induced by TGF-β1 Myofibroblast differentiation is
… The expression and organization of α-SMA is an indicator of myofibroblast differentiation. To …

… In this paper, we investigated the effects of PFD on TGF-β1-stimulated dermal … myofibroblast
differentiation and blocking either one of them can prevent myofibroblast differentiation …

… This study suggests that topical application of pirfenidone … of action may be the inhibition
of TGF-β1-induced epidural scar fibroblast proliferation and differentiation into myofibroblasts …

… to inhibit the initial differentiation of fibroblasts into myofibroblasts in vitro and act as a …
pirfenidone affects differentiated myofibroblasts, we investigated the in vitro effects of pirfenidone …

… Recently two drugs, pirfenidone and nintedanib, were approved for clinical use as they are
able … the effects of pirfenidone and nintedanib on fibroblasts and myofibroblasts structure and …