Major clinical outcomes in antiretroviral therapy (ART)–naive participants and in those not receiving ART at baseline in the SMART study
… for Management of Antiretroviral Therapy … - The Journal of …, 2008 - academic.oup.com
… The absence of randomized data in both the developed and developing world has required
antiretroviral treatment guidelines to rely on the interpretation of nonrandomized studies and …
antiretroviral treatment guidelines to rely on the interpretation of nonrandomized studies and …
Antiretroviral prescribing patterns in treatment-naive patients in the United States
JA McKinnell, JH Willig, AO Westfall… - AIDS Patient Care …, 2010 - liebertpub.com
… ARV treatment share. By 2007, only two unique regimens were used in the treatment of over
95% of patients starting ARV … in this patient population could be considered. Successfully …
95% of patients starting ARV … in this patient population could be considered. Successfully …
Minority HIV-1 drug resistance mutations are present in antiretroviral treatment–naïve populations and associate with reduced treatment efficacy
JA Johnson, JF Li, X Wei, J Lipscomb, D Irlbeck… - PLoS …, 2008 - journals.plos.org
… persons might reflect mutations that were once linked in oligoclonal populations and … naïve
populations, we then assessed the impact of low-frequency resistance mutations on treatment …
populations, we then assessed the impact of low-frequency resistance mutations on treatment …
… drug resistance mutations in chronically HIV–infected, treatment-naive patients: implications for routine resistance screening before initiation of antiretroviral therapy
RM Novak, L Chen, RD MacArthur… - Clinical infectious …, 2005 - academic.oup.com
… The population in this study had more advanced HIV disease and had a larger proportion of
… CDC study and is surprisingly high for a population with advanced disease. Both exceed the …
… CDC study and is surprisingly high for a population with advanced disease. Both exceed the …
Low-abundance drug-resistant viral variants in chronically HIV-infected, antiretroviral treatment–naive patients significantly impact treatment outcomes
BB Simen, JF Simons, KH Hullsiek… - The Journal of …, 2009 - academic.oup.com
… in an HIV-infected population enrolled more recently [ 8 , 9 ], which suggests that minor
drug-resistant variants are still a factor in antiretroviral therapy–naive populations. Further, in our …
drug-resistant variants are still a factor in antiretroviral therapy–naive populations. Further, in our …
Global trends in antiretroviral resistance in treatment-naive individuals with HIV after rollout of antiretroviral treatment in resource-limited settings: a global …
… treatment programmes. We aimed to estimate changes in the prevalence of HIV-1 drug
resistance in treatment-naive … Despite intending to select studies of drug-naive populations, our …
resistance in treatment-naive … Despite intending to select studies of drug-naive populations, our …
Antiretroviral therapy adherence among treatment-naive HIV-infected patients
… Population groups experiencing lower incidence of adherence in this study among
treatment-naive patients are consistent with that among treatment-experienced HIV-infected patients. …
treatment-naive patients are consistent with that among treatment-experienced HIV-infected patients. …
Drug resistance among drug-naive and first-line antiretroviral treatment-failing children in Cameroon
J Fokam, R Salpini, MM Santoro, V Cento… - The Pediatric …, 2011 - journals.lww.com
… population of drug-naive … ARV drug-naive HIV-infected mother whose serologic status was
unknown during pregnancy and even after the child's birth; therefore, the child was not treated …
unknown during pregnancy and even after the child's birth; therefore, the child was not treated …
Low prevalence of transmitted genetic drug resistance in a cohort of HIV infected naive patients entering antiretroviral treatment programs at two sites in northern …
… antiretroviral treatment has … antiretroviral treatment in northern South Africa. In the intervening
time, there is a possibility of resistance emergence and transmission to naïve populations …
time, there is a possibility of resistance emergence and transmission to naïve populations …
Prevalence of antiretroviral drug resistance and resistance-associated mutations in antiretroviral therapy-naive HIV-infected individuals from 40 United States cities
L Ross, ML Lim, Q Liao, B Wine, AE Rodriguez… - HIV clinical …, 2007 - Taylor & Francis
… Antiretroviral treatment guidelines may also indirectly … The population examined in this
study was of particular interest, because it was geographically diverse and included ART-naïve …
study was of particular interest, because it was geographically diverse and included ART-naïve …
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