Epigenetics in NAFLD/NASH: Targets and therapy
… the development of NAFLD [9]. The present review elaborately discusses the epigenetic
mechanisms involved in NAFLD/NASH and possible therapeutic targets and therapies aiming at …
mechanisms involved in NAFLD/NASH and possible therapeutic targets and therapies aiming at …
Current and future pharmacological therapies for NAFLD/NASH
Y Sumida, M Yoneda - Journal of gastroenterology, 2018 - Springer
… for NASH/NAFLD. This review presents the agents currently used in managing NASH/NAFLD
and their pharmacologic targets. It also provides an overview of NAFLD agents currently …
and their pharmacologic targets. It also provides an overview of NAFLD agents currently …
[HTML][HTML] Current treatment paradigms and emerging therapies for NAFLD/NASH
S Raza, S Rajak, A Upadhyay, A Tewari… - Frontiers in bioscience …, 2021 - ncbi.nlm.nih.gov
… , and gut microbiome, with regard to therapy for NASH. In particular, we focus the … therapeutic
targets for NASH. We highlight these targets aiming to optimize the future for NASH therapy…
targets for NASH. We highlight these targets aiming to optimize the future for NASH therapy…
Current options and future directions for NAFLD and NASH treatment
… NAFLD and NASH. Liver inflammation and cellular death, with or without fibrosis account for
the progression of NAFLD to NASH… important targets for the therapy of NAFLD and NASH. In …
the progression of NAFLD to NASH… important targets for the therapy of NAFLD and NASH. In …
Therapeutic landscape for NAFLD in 2020
BA Neuschwander-Tetri - Gastroenterology, 2020 - Elsevier
… valuable in establishing potential targets of therapy and proposing … (NAFLD). The hepatokine
fibroblast growth factor (FGF)21, discussed further later in this article, as a therapy for NASH…
fibroblast growth factor (FGF)21, discussed further later in this article, as a therapy for NASH…
Emerging therapeutic targets and experimental drugs for the treatment of NAFLD
… in pre-clinical models of NASH [25]. It has been implicated in the pathogenesis of NAFLD/NASH
and has been a target for pharmacotherapy in the treatment of NASH [25]. Elafibranor, a …
and has been a target for pharmacotherapy in the treatment of NASH [25]. Elafibranor, a …
Target therapies for NASH/NAFLD: from the molecular aspect to the pharmacological and surgical alternatives
M Finotti, M Romano, P Auricchio, M Scopelliti… - Journal of Personalized …, 2021 - mdpi.com
… In our contribution, we review the most recent pharmacological target therapies, the role
of bariatric surgery, and the impact of liver transplantation on the NAFLD outcome. …
of bariatric surgery, and the impact of liver transplantation on the NAFLD outcome. …
NASH and NAFLD: emerging drugs, therapeutic targets and translational and clinical challenges
N Alkhouri - Expert Opinion on Investigational Drugs, 2020 - Taylor & Francis
… of therapeutic agents to treat this epidemic; we anticipate the first FDA approval of a drug to
treat NASH … The pipeline for NASH therapeutics is rich and is the focus of this special issue of …
treat NASH … The pipeline for NASH therapeutics is rich and is the focus of this special issue of …
Evolving role for pharmacotherapy in NAFLD/NASH
SL Attia, S Softic, M Mouzaki - Clinical and translational science, 2021 - Wiley Online Library
… target bile … for NAFLD is still an active and highly-needed area of ongoing investigation.
This study suggests that in the future, patients with NAFLD will likely require combination therapy …
This study suggests that in the future, patients with NAFLD will likely require combination therapy …
Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH)
X Xu, KL Poulsen, L Wu, S Liu, T Miyata… - … and targeted therapy, 2022 - nature.com
… drugs specifically to treat NAFL/NASH, growing progress is being … therapeutic targets. In
this review, we discussed recent developments in etiology and prospective therapeutic targets, …
this review, we discussed recent developments in etiology and prospective therapeutic targets, …