Stimulation of 3D osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor

PM Tsimbouri, PG Childs, GD Pemberton… - Nature Biomedical …, 2017 - nature.com
… the nanovibrational setup was complex and lacked scalability. In our nanovibrational bioreactor,
… The bioreactor design incorporates a 13-piezo array, mounted on an aluminium base, …

The use of nanovibration to discover specific and potent bioactive metabolites that stimulate osteogenic differentiation in mesenchymal stem cells

T Hodgkinson, PM Tsimbouri, V Llopis-Hernandez… - Science …, 2021 - science.org
… use nanovibrational stimulation to induce osteogenic differentiation of mesenchymal stem
cells… were then magnetically attached to the nanovibration bioreactor in cell culture incubators. …

Nanoindentation Characteristics of Stem Cells Towards Osteogenic Differentiation in a Nanoscale Vibratory Bioreactor

RR Sarbandi, MM Khani, K Hassani… - BioNanoScience, 2024 - Springer
… In the present study, we utilized a custom-made nanovibrational bioreactor to induce the
osteogenic differentiation of HUC-MSCs. We then employed atomic force microscopy (AFM) to …

Nanovibrational stimulation of mesenchymal stem cells induces therapeutic reactive oxygen species and inflammation for three-dimensional bone tissue engineering

W Orapiriyakul, MP Tsimbouri, P Childs, P Campsie… - ACS …, 2020 - ACS Publications
… 24-well plates with our nanovibrational bioreactor by simply attaching them to a vibrating
top-plate with magnets. The use of standard consumables also enables cells to be cultured in …

Design, construction and characterisation of a novel nanovibrational bioreactor and cultureware for osteogenesis

P Campsie, PG Childs, SN Robertson, K Cameron… - Scientific reports, 2019 - nature.com
… Stimulation of 3d osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor.
Nature Biomedical Engineering 1, 758–770, https://doi.org/10.1038/s41551-017-0127-4 (…

Nanoscale vibration could promote tenogenic differentiation of umbilical cord mesenchymal stem cells

E Karimi, N Vahedi, RR Sarbandi, A Parandakh… - In Vitro Cellular & …, 2023 - Springer
… Here, we used nanovibration to induce the differentiation of MSCs toward the tenogenic
fate solely by the use of nanovibration and … Nanovibration bioreactor setup and calibration …

Control of cell behaviour through nanovibrational stimulation: nanokicking

SN Robertson, P Campsie… - … of the Royal …, 2018 - royalsocietypublishing.org
Nanovibrational stimulation of cell cultures can be applied using the novel bioreactor
platform described within this paper. This system has been developed through computer …

Nanovibrational stimulation for 3D osteogenesis in biphasic 3D scaffold; a new option for bone tissue engineering

W Orapiriyakul - 2020 - theses.gla.ac.uk
… in mesenchymal stem cells (MSCs) … NS bioreactor is challenging due to its mechanical
properties. The principle aim of this thesis is to develop the scaffold for nanovibrational bioreactor

[PDF][PDF] Design, construction and characterisation of a novel nanovibrational bioreactor and cultureware for osteogenesis

S Reid - core.ac.uk
… Stimulation of 3d osteogenesis by mesenchymal stem cells using a nanovibrational bioreactor.
Nature Biomedical Engineering 1, 758–770, https://doi.org/10.1038/s41551-017-0127-4 (…

Osteoblastogenic differentiation of mesenchymal stem cells through nanoscale stimulation: The conception of a novel 3D osteogenic bioreactor

GD Pemberton - 2015 - theses.gla.ac.uk
… In this chapter we begin to examine the construction of a 2D bioreactor which was used
to induce osteoblastogenesis in mesenchymal stem cells. In order to have confidence in the …