Therapeutic potential and challenges of natural killer cells in treatment of solid tumors

A Gras Navarro, AT Björklund, M Chekenya - Frontiers in immunology, 2015 - frontiersin.org
… Due to the mode of NK cell killing, requiring one-to-one … granules, the therapeutic potential
of NK cells has been most … coated cells, cancer stem cells, and genotoxically altered cells, …

Therapeutic potential of natural killer cells in gastric cancer

Y Du, Y Wei - Frontiers in immunology, 2019 - frontiersin.org
… Despite various therapeutic approaches, the cures and prognosis of advanced GC remain
poor. Natural killer (NK) cells, which are known as important lymphocytes in innate immunity, …

Natural killer cells: a review of biology, therapeutic potential and challenges in treatment of solid tumors

K Choucair, JR Duff, CS Cassidy, MT Albrethsen… - Future …, 2019 - Taylor & Francis
Natural killer (NK) cells lead immune surveillance against cancer and early elimination of …
need of specific antigen, the therapeutic potential of NK cells has been extensively explored in …

Natural killer cells in chronic lymphocytic leukemia: functional impairment and therapeutic potential

M Yano, JC Byrd, N Muthusamy - Cancers, 2022 - mdpi.com
therapies such as immune checkpoint blockade and CAR-T, recent advances in NK cell
therapy have highlighted the therapeutic potential of these cells. Chronic lymphocytic leukemia (…

The therapeutic potential of natural killer cells in neuropathic pain

HW Kim, S Wang, AJ Davies, SB Oh - Trends in Neurosciences, 2023 - cell.com
… In this opinion article, we set out the case for NK cell-based … the potential cellular and
molecular targets of NK cells in the … functions of NK cells and immune-based therapeutics in the …

The therapeutic potential of natural killer cells to target medulloblastoma

A Pérez-Martínez, L Fernández… - … of Anticancer Therapy, 2016 - Taylor & Francis
… -MB immunity and therapy. However, there is no clinical study regarding NK cell therapy on
patients suffering from MB or regarding the prognostic factor of NK cell infiltration into the MB […

Therapeutic potential of highly cytotoxic natural killer cells for gastric cancer

K Mimura, T Kamiya, K Shiraishi, LF Kua… - … journal of cancer, 2014 - Wiley Online Library
… To develop more effective therapies for patients with advanced gastric cancer, we examined
the potential of ex vivo expanded natural killer (NK) cells. We assessed the expression of …

[HTML][HTML] Therapeutic potential of natural killer cells in neuroimmunological diseases

Q Zhang, J Lin, M Yang, Z Li, M Zhang, B Bu - Biomedicine & …, 2024 - Elsevier
Natural killer (NK) cells, a major component of the … cells act as a double-edged sword with
therapeutic potential in neurological autoimmunity. Emerging evidence has identified NK cells

Human natural killer cells in health and disease: biology and therapeutic potential

TL Whiteside, RB Herberman - Clinical Immunotherapeutics, 1994 - Springer
… or replace NK cell activity is becoming available. Therapeutic modification of NK cell
activity is likely to become more widely used as our knowledge of the relevance of NK cells

[HTML][HTML] Immunoregulatory functions and therapeutic potential of natural killer cell-derived extracellular vesicles in chronic diseases

S He, L Su, H Hu, H Liu, J Xiong, X Gong… - Frontiers in …, 2024 - frontiersin.org
… NK cells derived from induced pluripotent stem cells (iPSC) have been shown to be
superior in cellular therapy compared to primary NK cells and the NK-92 cell line. The …