… Natural killer (NK) cells are effector lymphocytes of the innate immune system that control
several types of tumors and microbial infections by limiting their spread and subsequent tissue …

… Who was a pioneer in studies of natural cell-mediated resistance in mice … Herberman Large
Granular Lymphocytes as Effector Cells of Natural Killer Activity in the Mouse Aldo Tagliabue…

… effector cells that resemble natural killer (NK) cells have been part of the innate immune
defense system long before the arrival of the seemingly more sophisticated T and B cells of the …

… Natural killer (NK) cells have been originally characterized as cytolytic effector lymphocytes
present in mouse spleen and human peripheral blood. The “NK” name was originally coined …

… and kill other target cells. In particular, we are actively investigating whether LGL may be
the effector cell in mediating natural cytotoxicity (NC) activity against adherent target cells (27). …

… from the target cell donors. Natural killer (NK) effector cells were magnetically separated …
(Miltenyi Biotec) and added to the infected cells at an effector/target cell (E:T) ratio of 10:1 …

… Against suitable targets, the effect of NKG2D can be better appreciated by using NCR
dull NK cell clones as effector cells 26. Although the cellular ligands of NCR have not been …

… Natural killer (NK) cells and natural killer T (NKT) cells are subsets of lymphocytes that share
some phenotypical and functional similarities. Both cell … of their effector functions, migratory …

… cell function. We believe that a full understanding of how NK cells become activated and
develop their effector … have some degree of plasticity to become different effector cells, and also …

… Natural killer (NK) cells were originally defined by their ability to lyse tumor cells or virus-infected
cells and identified as one type of effector cells of the non-antigen specific innate …