Interferon-α–induced TRAIL on natural killer cells is associated with control of hepatitis C virus infection

KA Stegmann, NK Björkström, H Veber, S Ciesek… - Gastroenterology, 2010 - Elsevier
Natural killer (NK) cells might be associated with control of … Natural killer (NK) cells also
have been suggested to … for chronic hepatitis C is pegylated interferon-alfa (PEG–IFN-alfa) in …

Antiviral response by natural killer cells through TRAIL gene induction by IFNα

K Sato, S Hida, H Takayanagi, T Yokochi… - European journal of …, 2001 - Wiley Online Library
IFN-α/β production also affects other types of the immune responses, which include induction
of cytotoxic activity of natural killer (… It has been known that NK cells are activated by IFN-α/β …

Interferona major regulator of natural killer cell-mediated cytotoxicity

ZVI Reiter - Journal of interferon research, 1993 - liebertpub.com
… of natural killer cytotoxicity. III. Activation of NK cells by interferon augments the lytic activity
of released natural killer … Comparison of natural killer and natural killer cytotoxic cells: …

Interleukin‐1β costimulates interferon‐γ production by human natural killer cells

MA Cooper, TA Fehniger, A Ponnappan… - European journal of …, 2001 - Wiley Online Library
Natural killer (NK) cells are an early source of immunoregulatory cytokines during the
innate immune response to viruses, bacteria, and parasites. NK cells provide requisite …

Natural killer cells are polarized toward cytotoxicity in chronic hepatitis C in an interferon-alfa–dependent manner

G Ahlenstiel, RH Titerence, C Koh, B Edlich, JJ Feld… - Gastroenterology, 2010 - Elsevier
… We found an increased frequency of natural killer (NK) cells … , but with not increased interferon
(IFN)-γ production of CD56 … to HCV-induced type I IFN was causing this NK cell phenotype…

A comparison of interferon-Con1 with natural recombinant interferons-α: antiviral, antiproliferative, and natural killer-inducing activities

ON OZES, ZVI Reiter, S KLEIN, LM BLATT… - Journal of interferon …, 1992 - liebertpub.com
… However it has been reported that IFNConl has a specific antiviral activity 10-fold greater
than any natural IFN subtype tested to date.'5'7' IFN-a has been used successfully in the …

Natural killer cell‐mediated contact sensitivity develops rapidly and depends on interferonα, interferon‐γ and interleukin‐12

M Majewska‐Szczepanik, S Paust… - …, 2013 - Wiley Online Library
Natural killer ( NK ) cell‐mediated contact sensitivity was recently described in mice. Here,
we confirm NK cell‐mediated contact sensitivity ( CS ) in SCID and RAG 1 −/− mice but not in …

Low doses of interferon alpha result in more effective clinical natural killer cell activation.

BS Edwards, JA Merritt, RC Fuhlbrigge… - The Journal of …, 1985 - Am Soc Clin Investig
interferon (IFN) effects upon natural killer (NK) cells in vivo, we gave cancer patients serial
weekly intramuscular injections of purified lymphoblastoid IFN in … injection of IFN dosages a …

Interferon-α activates cytotoxic function but inhibits interleukin-2-mediated proliferation and tumor necrosis factor-α secretion by immature human natural killer cells

A Jewett, B Bonavida - Journal of clinical immunology, 1995 - Springer
IFN-c~ has been shown to upregulate natural killer activity but the mechanism by which such
upregulation occurs is not fully understood. IFN-c~ has been shown to decrease DNA, RNA…

A species of human alpha interferon that lacks the ability to boost human natural killer activity.

JR Ortaldo, RB Herberman, C Harvey… - Proceedings of the …, 1984 - National Acad Sciences
… ferons (IFN-aA, -aB, -aC, -aD, -aF, -61, and -aK) were capable of boosting human natural killer
(NK… In contrast, recombinant human IFN-azJ wasfound to be incapable of augmenting NK …