… Here, we have used this system to study natural killer (NK) cell … Interferon (IFN) α is necessary
for natural killer (NK) cell … (A), IFN-γ (B), and tumor necrosis factor (TNF) α (C) production of …

… Antibody neutralization studies indicated that FAA induced IFN of the α/β type, while … the
production of IFN a mRNA in splenic leukocytes. In vivo administration of anti-IFN α/β antibodies …

… mononuclear cells after interferon (IFN)-α/β … IFN-α/β-stimulated NK cytotoxicity compared
to adult mice. In contrast, adult and aged F 1 mice showed similar NK cytotoxicity after IFN-α/β …

… natural human interferon-c~ (IFN-c 0 partially eliminates this effect. Because natural IFN-c~
might contain factors other than IFN… experiments with recombinant human interferon-c~ (rhIFN…

… By analyzing the percentage of the increase in basal natural killer activity after interferon
a 2b treatment, we observed a value of 44.1% in responder patients versus 30.3% in …

… Natural killer (NK) activity of peripheral lymphocytes was measured in 39 patients … interferon
(IFN) therapy. NK activity increased in a majority of patients following the first injection of IFN …

… In the accompanying paper, we showed that natural killer (NK) … , interferon (IFN). In the
present study, therefore, we examined whether these cloned NK cells on their own produced IFN. …

… Implications: Natural killer cells can kill cancer cells and virally infected cells. This study …
decreased natural killer cell activity as assessed in the laboratory. This decreased natural killer …

… interferons. These results provide some insight into structure-activity relationships for stimulating
natural killer … to predict other activities for an individual IFN-a species. The observations …

… tumor cells, human IFN-α gene-modified natural killer cell line (NKL) (NKL-IFNα) cells, which
could stably secrete IFN-α, were established. We investigated the natural cytotoxicity of NKL…