Natural products as sources of new drugs over the nearly four decades from 01/1981 to 09/2019
DJ Newman, GM Cragg - Journal of natural products, 2020 - ACS Publications
… on sources of novel antibiotics from Nature due to the absolute … that a significant number of
natural product drugs/leads are … natural product research should be expanded significantly. …
natural product drugs/leads are … natural product research should be expanded significantly. …
Natural products as potential lead compounds to develop new antiviral drugs over the past decade
JH Zhao, YW Wang, J Yang, ZJ Tong, JZ Wu… - European Journal of …, 2023 - Elsevier
… microorganisms in nature with rich structural skeletons, and they are natural treasure house
… the natural products with antiviral activity that had been reported for the first time in the past …
… the natural products with antiviral activity that had been reported for the first time in the past …
Natural product discovery: past, present, and future
L Katz, RH Baltz - Journal of Industrial Microbiology and …, 2016 - academic.oup.com
… Over the past seven decades, natural product … next two decades. Overall efforts in NP
discovery have decelerated with the waning interest from the pharmaceutical industry over the past …
discovery have decelerated with the waning interest from the pharmaceutical industry over the past …
Natural products for cancer therapy: a review of their mechanism of actions and toxicity in the past decade
YO Ali Abdalla, B Subramaniam… - Journal of Tropical …, 2022 - Wiley Online Library
… Despite the positive attributes of natural products, there are many questions pertaining to …
on natural products that are recently been investigated extensively in the past decade for their …
on natural products that are recently been investigated extensively in the past decade for their …
Drug discovery and natural products: end of an era or an endless frontier?
JWH Li, JC Vederas - Science, 2009 - science.org
… However, many pharmaceutical firms have eliminated their natural product research in the
past decade. Although more than 100 natural product–based drugs are in clinical studies, this …
past decade. Although more than 100 natural product–based drugs are in clinical studies, this …
[HTML][HTML] Trends in the discovery of new marine natural products from invertebrates over the last two decades–where and what are we bioprospecting?
… discovery over the past two decades, taking … decades?. Beyond the importance of the
outcome of the present work for several research fields associated with marine natural products (…
outcome of the present work for several research fields associated with marine natural products (…
[PDF][PDF] Recent natural products based drug development: a pharmaceutical industry perspective
YZ Shu - Journal of natural products, 1998 - chem.uwec.edu
… mg bid43,44 In the antidiabetes area, the past decade has witnessed the market introduction
of several R-glucosidase inhibitors derived from natural products. Acarbose, a complex of …
of several R-glucosidase inhibitors derived from natural products. Acarbose, a complex of …
Natural products as sources of new drugs from 1981 to 2014
DJ Newman, GM Cragg - Journal of natural products, 2016 - ACS Publications
… (102) We have continued our attempts to capture vaccine data for the past few years, but …
and 30% in the other years of the second decade of the 21st century. The mean and standard …
and 30% in the other years of the second decade of the 21st century. The mean and standard …
[HTML][HTML] A historical overview of natural products in drug discovery
… In the past two decades “classical natural product chemistry” has largely been replaced by
molecular target based drug discovery, utilizing large combinatorial libraries to obtain efficient …
molecular target based drug discovery, utilizing large combinatorial libraries to obtain efficient …
[HTML][HTML] Discovery and resupply of pharmacologically active plant-derived natural products: A review
AG Atanasov, B Waltenberger… - Biotechnology …, 2015 - Elsevier
… In the past decades, pharmaceutical industry focused mainly … interest in drug discovery
from natural sources, despite of its … to plant-derived natural product drug discovery. Associated …
from natural sources, despite of its … to plant-derived natural product drug discovery. Associated …
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