Identifying regions of the human genome that have been targets of natural selection will …
disease genes. Although the signature that natural selection imparts on DNA sequence variation …

… In sexual organisms, little is known about the molecular population genetics of adaptation …
sizes and natural selection at the genotype level. We demonstrate that selection has occurred …

… Natural selection is further suggested as the major determinant of genetic variation in
green toads, by testing the distribution of gene frequency directly (3). Significant heterogeneity …

… the correlation between neutral genetic diversity and recombination rate. This work suggests
that natural selection has affected multiple aspects of linked neutral variation throughout the …

… there is genetic variation among males for the degree of this harm. Genetic variation among
… Overall this study documents strong selection for female resistance to harm from males and …

… shape this variation 3 . The situation is far less clear, however, for genetic variation that affects
… What are the roles of genetic drift or various forms of natural selection in determining the …

… for positive natural selection in the European sample: (i) a large number of loci with low levels
of variation and (ii) a significant excess of derived variants at the low-variation loci that are …

… analyses suggested that such high levels of genetic variation in … selection in this population.
Hence, our original expectation (low levels of genetic variation, strong directional selection) …

… We analyzed variation in individual reaction norms between laying date and three climatic
… Variation in laying date was best explained by local temperature, and individual females …

… is knowledge of the genetic basis of traits likely to be under selection in a dynamically …
of genetic variation is modulated and shaped by the action of natural selection in the natural …