Systematically benchmarking peptide-MHC binding predictors: From synthetic to naturally processed epitopes
W Zhao, X Sher - PLoS computational biology, 2018 - journals.plos.org
… ligandome, the reliability of new predictors on these epitopes has yet … MHC-binding predictors
by using newly available, untested data of both synthetic and naturally processed epitopes…
by using newly available, untested data of both synthetic and naturally processed epitopes…
Deciphering the MHC-associated peptidome: a review of naturally processed ligand data
… Areas covered: For this, we first analyzed naturally processed peptide (NP) … peptides were
also reported to be T cell epitopes. Thus, the NP data identify only a small subset of epitopes …
also reported to be T cell epitopes. Thus, the NP data identify only a small subset of epitopes …
MHC-NP: predicting peptides naturally processed by the MHC
… We present MHC-NP, a tool for predicting peptides naturally processed by the MHC pathway…
Our tool is freely available online and hosted by the Immune Epitope Database at http://tools.…
Our tool is freely available online and hosted by the Immune Epitope Database at http://tools.…
Post-translational modifications of naturally processed MHC-binding epitopes
VH Engelhard, M Altrich-Vanlith, M Ostankovitch… - Current opinion in …, 2006 - Elsevier
… identified in naturally processed MHC-associated peptides, the relationship of PTMs to antigen
… involving disulfide bond formation within naturally processed MHC associated peptides. …
… involving disulfide bond formation within naturally processed MHC associated peptides. …
… processed HLA class II peptides reveal highly conserved immunogenic flanking region sequence preferences that reflect antigen processing rather than peptide-MHC …
AJ Godkin, KJ Smith, A Willis… - The Journal of …, 2001 - journals.aai.org
… MHC class II ligands. There is evidence that addition of C-terminal basic PFRs to known
peptide epitopes is able to enhance both processing … epitope identification and vaccine design. …
peptide epitopes is able to enhance both processing … epitope identification and vaccine design. …
Naturally processed peptides longer than nine amino acid residues bind to the class I MHC molecule HLA-A2. 1 with high affinity and in different conformations.
… epitope HIVenv,,,-,,, (26), and the HLA-A1 restricted peptide epitope Mage-1 … In the current
study, the relative affinities of naturally processed peptides for the class I MHC molecule HLA-…
study, the relative affinities of naturally processed peptides for the class I MHC molecule HLA-…
MHC Class I-Restricted Antigen Processing—Lessons from Natural Ligands
HG Rammensee, O Rötzschke, K Falk - Naturally Processed Peptides, 1993 - karger.com
… MHC Class I-Restricted Antigen Processing 115 of naturally processed T cell epitopes is to
compare them with synthetic peptides, which is possible if the protein of origin is known. For …
compare them with synthetic peptides, which is possible if the protein of origin is known. For …
Structure of peptides associated with class I and class II MHC molecules
VH Engelhard - Annual review of immunology, 1994 - annualreviews.org
… of the complexity of naturally processed peptides associated with MHC molecules. Greater
… An important extension of this work is the identification of MHC-restricted peptide epitopes …
… An important extension of this work is the identification of MHC-restricted peptide epitopes …
Footprints of antigen processing boost MHC class II natural ligand predictions
… of peptide to MHC-II binding trained with naturally … a naturally processed ligand, we can
assume that the sequence of the validated epitope and the original (but unknown to us) naturally …
assume that the sequence of the validated epitope and the original (but unknown to us) naturally …
Peptide HER2 (776–788) represents a naturally processed broad MHC class II-restricted T cell epitope
R Sotiriadou, SA Perez, AD Gritzapis… - British Journal of …, 2001 - nature.com
… 788) as a helper epitope and the identification of its potential promiscuity (broad MHC restriction),
so as … We report here that HER2(776–788) is a helper peptide naturally processed and …
so as … We report here that HER2(776–788) is a helper peptide naturally processed and …
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