… Certain tumor types were more common in our study, but most tumor types were represented
only as single cases. All 6 patients with gynecologic primaries seemed to derive clinical …

… Assignment to treatment in NCI-MATCH depended on whether the substudy was open or
closed in general, and for the patient’s tumor type in particular—as some tumors were more …

… Background: Certain tumor types show dramatic responses to targeted treatments based …
NCI-MATCH study hypothesizes that patients (pts) across a range of histologies whose tumors …

… Although we have not yet compared the NCI-MATCH specimens with the patients’ primary
tumors, the available data from TCGA and NCI-MATCH suggest there is not substantial …

… to NCI MATCH, patients undergo tumor biopsies at the time of enrollment with the tumor …
Distinct from NCI MATCH, patients for whom an actionable mutation is detected undergo a 2:1 …

… The experiences in the design and implementation of the NCI-MATCH trial suggest that
profiling from fresh tumor biopsies and assigning treatment can be performed efficiently in a …

… patient treatment assignments. The purpose of this review is to offer an update on the current
status of NCI-MATCH, … In sub-protocol Arm I of NCI-MATCH, patients who had tumors with …

… of the rare tumors listed above, our data suggest that patients with other tumor types that …
First, this was a pre-treated population with most patients having received at least 2 lines of …

… across multiple tumor types. The NCI-MATCH (EAY131) is a tumor-agnostic platform trial
that enrolls patients to targeted therapies on the basis of matching genomic alterations. Arm …

… that induced tumor responses in … patients selected based on their tumors’ genomic
profile and tissue of origin. Here we report the results of one of the subprotocols of the NCI-MATCH …