Human papillomavirus genome integration and head and neck cancer

LM Pinatti, HM Walline… - Journal of dental …, 2018 - journals.sagepub.com
papillomavirus (HPV) integration into the host genome in oral/oropharyngeal cancer, reviewed
the literature for HPV-induced cancers… related oral and oropharyngeal cancers. In addition…

[HTML][HTML] Integration of human papillomavirus genomes in head and neck cancer: is it time to consider a paradigm shift?

IM Morgan, LJ DiNardo, B Windle - Viruses, 2017 - mdpi.com
… (HNC) are episomal, integrated and virus–human hybrid … tumors that have both episomal
and integrated viral genomes [1]. … of HPV integration in head and neck cancer and explain why …

Human papillomavirus integration strictly correlates with global genome instability in head and neck cancer

B Labarge, M Hennessy, L Zhang, D Goldrich… - Molecular Cancer …, 2022 - AACR
… Our results indicate that HPV integration in head and neck cancer correlates with extensive
… Thus, the difference between integrating and non-integrating viruses in our cohort does not …

Human papilloma virus integration sites and genomic signatures in head and neck squamous cell carcinoma

J Mainguené, S Vacher, M Kamal, A Hamza… - Molecular …, 2022 - Wiley Online Library
… A prevalence of around 26% of human papillomavirus (HPV) in head and neck
squamous cell … More than 90% of head and neck cancers are squamous cell carcinomas (HNSCC), …

Integration of high‐risk human papillomavirus into cellular cancer‐related genes in head and neck cancer cell lines

, … Michigan Head and Neck Specialized Program of … - … & neck, 2017 - Wiley Online Library
… genomic site of viral integration in 8 head and neck and 1 cervical cancer HPV-induced
human tumor cell lines, and determined the effect of viral integration on effected host genes. …

Association of human papillomavirus integration with better patient outcomes in oropharyngeal squamous cell carcinoma

LM Pinatti, HN Sinha, CV Brummel, CM Goudsmit… - … & neck, 2021 - Wiley Online Library
… , but there is a growing body of literature implicating integration as a potentially useful
biomarker in head and neck cancer. It has been debated whether integration is a stochastic …

Human papillomavirus type 16 (HPV-16) genomes integrated in head and neck cancers and in HPV-16-immortalized human keratinocyte clones express chimeric …

MJ Lace, JR Anson, JP Klussmann, DH Wang… - Journal of …, 2011 - Am Soc Microbiol
papillomavirus (HPV)-positive high-grade lesions and cancers of the uterine cervix harbor
integrated … , but less is known about HPV integration in head and neck cancer (HNC). Here we …

Mapping and analysis of HPV16 integration sites in a head and neck cancer cell line

CCR Ragin, SC Reshmi… - … journal of cancer, 2004 - Wiley Online Library
… with human papillomavirus (HPV). HPV targets the epithelial mucosa and frequently integrates
… Moreover, a breakpoint within the HPV E1/E2 sequence allows integration of HPV into its …

[HTML][HTML] Human Papillomavirus 16 DNA Methylation Patterns and Investigation of Integration Status in Head and Neck Cancer Cases

I Zygouras, D Leventakou, A Pouliakis… - International Journal of …, 2023 - mdpi.com
integration of HPV16 virus in cervical cancer, there remains a scarcity of investigations
concerning epigenetic alterations of HPV16 in head and neck cancers. … to oropharyngeal cancer […

HPV integration in head and neck squamous cell carcinomas: cause and consequence

EJM Speel - HPV infection in head and neck cancer, 2017 - Springer
… with the HPV integration status of head and neck cancers. In the first study, Parfenov et al.
(2014) showed that DNA methylation profiles are distinct for HPV-positive tumors with …