[HTML][HTML] Mechanisms of resistance in head and neck cancer

H Picon, AK Guddati - American journal of cancer research, 2020 - ncbi.nlm.nih.gov
Resistance to radiation therapy is called radiation resistance and has been observed in
HNSCC. Intrinsic resistanceresistance will lead to novel approaches to cancer therapies and …

Role of autophagy in head and neck cancer and therapeutic resistance

MK Sannigrahi, V Singh, R Sharma, NK Panda… - Oral …, 2015 - Wiley Online Library
… and overcoming therapeutic resistance in HNSCC. … therapeutic resistance, the combination
of autophagy inducer or inhibitors with cytotoxic drugs may be used for cancer therapy based …

[HTML][HTML] Hypoxia-induced therapy resistance: Available hypoxia-targeting strategies and current advances in head and neck cancer

VL Codony, M Tavassoli - Translational oncology, 2021 - Elsevier
… pressure hypoxia exerts on cancer cells, leads to the propagation of more aggressive and
stress-resistant subpopulations increasing therapy resistance and worsening patient outcomes…

[HTML][HTML] Targeting stress-response pathways and therapeutic resistance in head and neck cancer

T Bos, JA Ratti, H Harada - Frontiers in Oral Health, 2021 - frontiersin.org
… , Massey Cancer Center, Virginia Commonwealth University, Richmond, VA, United States
Head and neck cancer is the sixth leading cancer worldwide; head and neck squamous cell …

[HTML][HTML] Precision medicine approaches to overcome resistance to therapy in head and neck cancers

S Ortiz-Cuaran, J Bouaoud, A Karabajakian… - Frontiers in …, 2021 - frontiersin.org
… of therapy resistance is … of resistance to the therapeutic strategies currently used in HNSCC,
discuss combination treatment strategies to overcome them, and summarize the therapeutic

[HTML][HTML] Epigenetic modifications and head and neck cancer: implications for tumor progression and resistance to therapy

RM Castilho, CH Squarize, LO Almeida - International journal of …, 2017 - mdpi.com
… intrinsic or acquired therapy resistance, and … neck carcinogenesis, and the prospective
identification of epigenetic markers associated with CSCs, hold the promise for novel therapeutic

[HTML][HTML] Molecular mechanisms of chemotherapy resistance in head and neck cancers

Y Kanno, CY Chen, HL Lee, JF Chiou… - Frontiers in …, 2021 - frontiersin.org
resistance is a huge barrier for head and neck cancer (HNC) … mechanisms of chemotherapy
resistance that occur during … conventional therapies with previous cancer treatments such …

Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction

AK Gupta, WG McKenna, CN Weber, MD Feldman… - Clinical Cancer …, 2002 - AACR
… Accelerated fractionation (AF) compared to conventional fractionation (CF) improves loco-regional
control in the radiotherapy of advanced head and neck cancers: results of EORTC …

Targeting cellular metabolism in head and neck cancer precision medicine era: A promising strategy to overcome therapy resistance

X Lin, W Zhou, Z Liu, W Cao, C Lin - Oral Diseases, 2023 - Wiley Online Library
… the response of drug-resistant tumors to anticancer therapy. This review will provide a better
… in therapy resistance of HNSCC and promote the development of new therapeutic strategies …

Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer

SB Keysar, PN Le, RT Anderson, JJ Morton… - Cancer research, 2013 - AACR
… Acquired resistance to EGFR inhibition is common. Previous reports synergistically linked …
a mechanism for EGFR resistance in HNSCC. Sensitivity to anti-EGFR therapy was previously …