Characterization of HPV and host genome interactions in primary head and neck cancers
…, Cancer Genome Atlas Network - Proceedings of the …, 2014 - National Acad Sciences
… neck cancers have not been comprehensively described. We profiled a cohort of 279 head
and neck cancers … %) tumors displayed evidence of high-risk HPV types 16, 33, or 35. Twenty-…
and neck cancers … %) tumors displayed evidence of high-risk HPV types 16, 33, or 35. Twenty-…
Characterization of human papillomavirus antibodies in individuals with head and neck cancer
KAL Kuhs, M Pawlita, SP Gibson, NC Schmitt… - Cancer …, 2016 - Elsevier
… We tested 260 incident head and neck cancers for HPV … -OPC) incident head and neck
cancers diagnosed at the University of … Sensitivity and specificity of HPV16 E6 antibodies for HPV-…
cancers diagnosed at the University of … Sensitivity and specificity of HPV16 E6 antibodies for HPV-…
Development and characterization of HPV-positive and HPV-negative head and neck squamous cell carcinoma tumorgrafts
… We describe and characterize a direct-from-patient tumorgraft model system of human head
… of HPV infection in head and neck cancer, we assessed the HPV status of all tumorgrafts. …
… of HPV infection in head and neck cancer, we assessed the HPV status of all tumorgrafts. …
[HTML][HTML] Identification and characterization of HPV-independent cervical cancers
CE Banister, C Liu, L Pirisi, KE Creek, PJ Buckhaults - Oncotarget, 2017 - ncbi.nlm.nih.gov
… neck cancers [7], we identified a subset of tumors, which no longer express HPV E6/E7
oncogenes (HPV-… from HPV-active tumors, and more similar to those of other, viral-independent …
oncogenes (HPV-… from HPV-active tumors, and more similar to those of other, viral-independent …
Subtypes of HPV-positive head and neck cancers are associated with HPV characteristics, copy number alterations, PIK3CA mutation, and pathway signatures
… Conclusions: Our characterization of two subtypes of HPV + HNC tumors provides valuable
molecular level information that point to two main carcinogenic paths. Together, these results …
molecular level information that point to two main carcinogenic paths. Together, these results …
Epidemiology and clinical aspects of HPV in head and neck cancers
AK Chaturvedi - Head and neck pathology, 2012 - Springer
… etiologic role of HPV infection in other head and neck cancers, such as sinonasal cancers
and … In contrast, HPV-positive oropharyngeal cancers are characterized by a younger age at …
and … In contrast, HPV-positive oropharyngeal cancers are characterized by a younger age at …
Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes
… HPV + head and neck cancer and two subtypes (one HPV + and one HPV − ) with a prominent
immune phenotype characterized … development for head and neck cancer and will inform …
immune phenotype characterized … development for head and neck cancer and will inform …
[HTML][HTML] HPV & head and neck cancer: a descriptive update
PKC Goon, MA Stanley, J Ebmeyer, L Steinsträsser… - Head & neck …, 2009 - Springer
… of head and neck cancers. Several studies indicate that oral human papillomavirus (HPV)
infection is likely to be sexually acquired. The dominance of HPV 16 in HPV+ HNSCC is even …
infection is likely to be sexually acquired. The dominance of HPV 16 in HPV+ HNSCC is even …
[HTML][HTML] HPV and head and neck cancers: Towards early diagnosis and prevention
… characterized for HPV-related HNSCC. Therefore, identification of general diagnostic
algorithms and HPV … for HPV-driven HNSCCs are urgently needed. We herein review the role of …
algorithms and HPV … for HPV-driven HNSCCs are urgently needed. We herein review the role of …
HPV as a marker for molecular characterization in head and neck oncology: looking for a standardization of clinical use and of detection method (s) in clinical practice
… an HPV diagnostic tool probably led many studies to overestimate the real clinical relevance
of HPV infection in head and neck cancers, … statistical correlation with HPV infection and has …
of HPV infection in head and neck cancers, … statistical correlation with HPV infection and has …
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