Effects of a polymorphism in the human tumor necrosis factor α promoter on transcriptional activation

AG Wilson, JA Symons, TL McDowell… - Proceedings of the …, 1997 - National Acad Sciences
… a direct functional effect of any polymorphism, because the … that the polymorphism at −308
has a significant effect on … at the polymorphic site, the interaction of transcription factors is …

Tumour necrosis factor gene polymorphism and disease prevalence

T Qidwai, F Khan - Scandinavian journal of immunology, 2011 - Wiley Online Library
… Tumour necrosis factor promoter polymorphism and susceptibility to falciparum malarial
infection and pulmonary tuberculosis have been carried out in Indian population. In malaria, TNF…

The− 308 tumor necrosis factor-α promoter polymorphism effects transcription

KM Kroeger, KS Carville, LJ Abraham - Molecular immunology, 1997 - Elsevier
… , the purpose of this study was to investigate whether the -308 polymorphism was able to
effect expression of the TNF-c( gene. We have investigated whether the -308 polymorphism

Effects of a single nucleotide polymorphism on the expression of human tumor necrosis factor‐alpha

K Lv, R Chen, Q Cai, M Fang… - Scandinavian journal of …, 2006 - Wiley Online Library
… These results show that this polymorphism may have a direct effect on TNF-α regulation in a
… from the polymorphism at −857 in the TNF-α promoter, there may be other factors affecting …

Association between− G308A tumor necrosis factor alpha gene polymorphism and schizophrenia

F Boin, R Zanardini, R Pioli, CA Altamura, M Maes… - Molecular …, 2001 - nature.com
polymorphism in 84 schizophrenic patients and in 138 healthy volunteers. This biallelic base
exchange polymorphism … 308 tumour necrosis factor promoter polymorphism and bronchial …

Effects of tumor necrosis factor gene polymorphisms on patients with congestive heart failure

T Kubota, DM McNamara, JJ Wang, M Trost… - Circulation, 1998 - Am Heart Assoc
… To examine the effects of TNF polymorphisms on susceptibility to CHF, we studied a series
… To examine the effects of TNF polymorphisms on circulating levels of TNF-α, we studied 211 …

Tumour-necrosis factor-A polymorphisms and gastric cancer risk: a meta-analysis

F Gorouhi, F Islami, H Bahrami, F Kamangar - British journal of cancer, 2008 - nature.com
… the association of polymorphisms in tumour-necrosis factor-A … -A polymorphisms and gastric
cancer risk. We analysed available data for the most commonly investigated polymorphisms: …

Different effects of polymorphisms of tumor necrosis factor‐alpha and interleukin‐1 beta on development of peptic ulcer and gastric cancer

M Sugimoto, T Furuta, N Shirai… - Journal of …, 2007 - Wiley Online Library
… Background and Aim: In Western countries, polymorphism of pro-inflammatory cytokine
genes … the association of polymorphisms of interleukin (IL)-1β and tumor necrosis factor (TNF)-α …

Polymorphisms of the tumour necrosis factor‐α gene, coronary heart disease and obesity

Herrmann, Ricard, Nicaud, Mallet… - European journal of …, 1998 - Wiley Online Library
… An allelic polymorphism within the human tumour necrosis factor-a promoter region is
strongly associated with HLA A1, B8, DR3 alleles. Journal of Experimental Medicine, 1993; 177: …

Tumour necrosis factor alpha gene polymorphisms in rheumatoid arthritis: association with susceptibility to, or severity of, disease?

BM Brinkman, TW Huizinga, SS Kurban… - British journal of …, 1997 - academic.oup.com
… strong effects on gene expression [14]. In this study, the frequencies of the known TNF-a
polymorphisms … In addition, we determined whether TNF-a polymorphisms are associated with …