… Group C were four asymptomatic seropositive individuals (ELISA; gag, pol, and env positive
… the seropositive to the seronegative state was also investigated. HIV-1 seropositivity was …

… Antibody responses against the nef gene product of HIV-1 were determined in … -seropositive
individuals and 72 individuals who seroconverted for antibodies to HIV-1 structural proteins (…

… expressed regulatory viral proteins, such as NEF, may … of NEF-specific human CTL in most
seropositive asymptomatic donors, and we identified a remarkable peptide within this protein. …

… recognized by sera from seropositive HIV-1 -infected individuals by the peptide … ” individuals,
with no antibodies to HIV structural proteins but reacting with the recombinant NfF protein in …

… -1 NEF protein recognized by cytotoxic T lymphocytes of seropositive individuals in association
… An antigenic peptide of the HIV-1 NEF protein recognized by cytotoxic T lymphocytes of …

… and 16 were in Nef. The percentages of peptides targeted within the individual proteins were
highly … was observed only for the proteins Gag-p17, Gag-p24, Gag-p15, and Nef. These four …

… nef could be detected among seronegative individuals at high risk for HIV infection long
before the appearance of antibodies to viral structural proteins… of nef serology in HIV-seropositive …

… nef deletions were revealed by length polymorphism analysis in samples from all three time
points. Sequence analysis of the nef … acquired HIV-1 seropositivity through the sexual route. …

… d Approximate time that elapsed between individuals first tested seropositive and when
CD4 T-cell counts first declined to less than 100/l, and the year of this decline are shown. …

… As polyclonal Abs to HIV-I Ags, the serum from an HIV-1-seropositive subject was used. In
… PBMCs from HIV-1-positive individuals by purified Nef. The PBMCs from two asymptomatic …