[HTML][HTML] Gleevec (STI-571) inhibits lung cancer cell growth (A549) and potentiates the cisplatin effect in vitro

P Zhang, WY Gao, S Turner, BS Ducatman - Molecular cancer, 2003 - Springer
… to investigate if Gleevec has a potential role in treatment of non-small cell lung cancer. …
culture condition is unlikely to be translated to clinical patients, since the adverse effects of the …

[HTML][HTML] Anti-cancer effects of baicalein in non-small cell lung cancer in-vitro and in-vivo

MC Cathcart, Z Useckaite, C Drakeford, V Semik… - BMC cancer, 2016 - Springer
… The negative effect on angiogenesis proteins lends support to earlier … cell lung cancer cells
H-460 (large cell carcinoma), A549 (adenocarcinoma) and SKMES1 (squamous carcinoma) …

Akt/protein kinase B is constitutively active in non-small cell lung cancer cells and promotes cellular survival and resistance to chemotherapy and radiation

J Brognard, AS Clark, Y Ni, PA Dennis - Cancer research, 2001 - AACR
… of LY294002 and chemotherapy on NSCLC apoptosis were specific for inhibiting Akt/PKB
activity, we transiently cotransfected NSCLC cell lines with HA-tagged dominant negative Akt/…

… of circulating tumor cells combined with negative enrichment and CD45-FISH identification in diagnosis, therapy monitoring and prognosis of primary lung cancer

YY Chen, GB Xu - Medical Oncology, 2014 - Springer
cell carcinoma (SCC) and other non-small cell lung cancer while … Among primary lung cancer
patients, small cell lung cancer … ’ positive rate than non-small cell cancer patients (Table 3). …

[HTML][HTML] Curcumin blocks small cell lung cancer cells migration, invasion, angiogenesis, cell cycle and neoplasia through Janus kinase-STAT3 signalling pathway

CL Yang, YY Liu, YG Ma, YX Xue, DG Liu, Y Ren… - PloS one, 2012 - journals.plos.org
… with less severe side effects is of great necessity. In clinical treatment of cancer patients,
many … has anticancer effects against different types of human tumor cells, including of ovarian …

Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo

T Sethi, RC Rintoul, SM Moore, AC MacKinnon… - Nature medicine, 1999 - nature.com
… the treatment of small cell lung cancer (… negative regulation of interleukin-1β converting
enzyme expression 6 , an essential effector of apoptosis. A characteristic feature of cancer cells is …

[HTML][HTML] Phloretin exhibits an anticancer effect and enhances the anticancer ability of cisplatin on non-small cell lung cancer cell lines by regulating expression of …

L Ma, R Wang, Y Nan, W Li… - … Journal of Oncology, 2015 - spandidos-publications.com
… patients because research has shown that these therapeutic agents had no side effects,
or at least the side effects were much more moderate compared with that of clinical first line …

[HTML][HTML] MiR-29c reduces the cisplatin resistance of non-small cell lung cancer cells by negatively regulating the PI3K/Akt pathway

D Sun, B Tang, Z Li, H Guo, J Cheng, P Song… - Scientific reports, 2018 - nature.com
effect of … lung cancer cells, finding that cisplatin can enhance miR-29c expression. Then,
a CCK8 assay was performed to measure the lung cancer cell viability upon cisplatin treatment

… kinase Cε is overexpressed in primary human non–small cell lung cancers and functionally required for proliferation of non–small cell lung cancer cells in a p21/Cip1 …

KM Bae, H Wang, G Jiang, MG Chen, L Lu, L Xiao - Cancer research, 2007 - AACR
… primary human non–small cell lung cancers (NSCLC) compared with normal lung epithelium.
We found that genetic inhibition of PKCε by expressing a dominant-negative mutant led to …

Inhibitory effect of Disulfiram/copper complex on non-small cell lung cancer cells

L Duan, H Shen, G Zhao, R Yang, X Cai… - Biochemical and …, 2014 - Elsevier
… to NSCLC cells partially through targeting lung cancer stem like cells. More importantly,
clinical experience with disulfiram in the treatment of alcoholism shows that side effects of …