Notch signaling induces cell cycle arrest in small cell lung cancer cells

V Sriuranpong, MW Borges, RK Ravi, DR Arnold… - Cancer research, 2001 - AACR
… Among the various forms of human lung cancer, small cell lung cancer (SCLC) exhibits a …
In nervous system development, the Notch signaling pathway is a critical negative regulator …

Isolated tumor cells in bone marrow predict reduced survival in node-negative non-small cell lung cancer

B Passlick, B Kubuschok, JR Izbicki, O Thetter… - The Annals of thoracic …, 1999 - Elsevier
… It recently became evident that isolated tumor cells undetectable by conventional tumor
-small cell lung cancer (NSCLC). The clinical relevance of this minimal hematogenous tumor cell

Inhibition of human telomerase enhances the effect of chemotherapeutic agents in lung cancer cells

M Misawa, T Tauchi, G Sashida… - International …, 2002 - spandidos-publications.com
… We introduced vectors encoding dominant negative (DN)-hTERT, or wild-type (WT)-hTERT, …
lung cancer cell line, and assessed the biological effect of telomerase inhibition on cellular

Gram negative bacteria increase non‐small cell lung cancer metastasis via toll‐like receptor 4 activation and mitogen‐activated protein kinase phosphorylation

SC Chow, SD Gowing… - … journal of cancer, 2015 - Wiley Online Library
Lung cancer cells have recently been demonstrated to express Toll-like receptors (TLR) …
cell lung cancer (NSCLC) cells with heat-inactivated Escherichia coli can augment cancer cell

In vitro toxic effects of reduced graphene oxide nanosheets on lung cancer cells

TA Tabish, MZI Pranjol, H Hayat, AAM Rahat… - …, 2017 - iopscience.iop.org
… several adverse effects in vitro including reactive oxygen species formation, cell apoptosis,
… This paper reports the in vitro toxic effects of rGO on lung cancer cells (A549 and SKMES-1) …

Ocimum sanctum induces apoptosis in A549 lung cancer cells and suppresses the in vivo growth of lewis lung carcinoma cells

V Magesh, JC Lee, KS Ahn, HJ Lee… - … Journal Devoted to …, 2009 - Wiley Online Library
… Although there are various therapies to treat lung cancer including chemotherapy and …
cause undesirable side effects. Therefore, new drugs without significant adverse side effects are …

MiR-155 inhibits the sensitivity of lung cancer cells to cisplatin via negative regulation of Apaf-1 expression

YS Zang, YF Zhong, Z Fang, B Li, J An - Cancer gene therapy, 2012 - nature.com
… microRNA in lung cancers, but information about the molecular mechanisms is still limited. …
the treatment of lung cancers, but resistance to cisplatin and its severe toxic side-effects limit …

Effect and mechanism of ginsenoside Rg3 on postoperative life span of patients with non-small cell lung cancer

P Lu, W Su, Z Miao, H Niu, J Liu, Q Hua - Chinese Journal of Integrative …, 2008 - Springer
… Shenyi effect, and the adverse reactions were observed. The pretreatment evaluation time
was within 1 week before chemotherapy, or 2-4 weeks postoperation. The post-treatment time …

The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy

GS Warshamana-Greene, J Litz, E Buchdunger… - Clinical cancer …, 2005 - AACR
… Given the potential for the effectiveness of IGF-IR signaling inhibitors in cancer treatment, it
is … Given that the side effect profile of these agents is likely to be different, the expectation that …

New insights into small‐cell lung cancer development and therapy

Y Wang, S Zou, Z Zhao, P Liu, C Ke… - Cell Biology …, 2020 - Wiley Online Library
… To reduce the adverse effect, … The lung cancer cells with high level of CD133 were quite
resistant to chemotherapeutics drugs, and the expression of CD133 was elevated after treatment