… validate the anti-proliferative effect of JAM-A inhibition in lung cancer cells. In agreement with
… of colony formation of the 2 tested lung cancer cell lines (negative control vs. JAM-A siRNA, …

… in lung cancer being associated with a quarter of the cancer … type of lung cancer, non-small
cell lung cancer (NSCLC) … , large-cell carcinoma and squamous-cell carcinoma while …

… for small-cell lung cancer, as they do not have the side-effects of the … their effects on small-cell
lung cancer cells and DNA synthesis. We further examined the small-cell lung cancer cells …

… side effects of lung cancer treatment with classic chemotherapeutic agents has led researchers
to find more efficient drugs with fewer side effects [5, 6]. … It has been shown that the cell …

… suggest that this tumour may be enriched in cells with cancer stem cell-like characteristics. …
of cancer stem-like cells in small-cell lung cancer. The existence of cancer stem cells was …

… associated with more side effects. For … treatment, serious adverse events should prompt a
change in agents. Therapy should also be stopped if the cancer grows or if, after four treatment …

… of cells and animal models to minimize their adverse effects and risks to the off-target living
organisms and tissues. The assessment of biosafety and biocompatibility of graphene will …

… Our findings demonstrate that CDDP activates Akt, which in turn negatively regulates the
apoptotic response to DNA damage. Targeted inhibition of Akt may thus have potential to …

… with the known detrimental effect of PD-L1 expression on survival [14] and with what was
observed previously [9]. One explanation might rely on the detrimental effect of CTCs, …

… impact of neoadjuvant chemotherapy (NACT) on PD-L1 expression in non-small cell lung
cancer (… ) method in 32 paired tumor specimens pre and post-NACT. The positivity of PD-L1 on …