Luteolin induced G2 phase cell cycle arrest and apoptosis on non-small cell lung cancer cells

X Cai, T Ye, C Liu, W Lu, M Lu, J Zhang, M Wang… - Toxicology in vitro, 2011 - Elsevier
… -cell lung carcinoma cell line A549 as a model to examine the therapeutic effects of luteolin.
… Untreated cells were primarily Annexin V-FITC and PI negative, indicating that they were …

Implication of the insulin-like growth factor-IR pathway in the resistance of non–small cell lung cancer cells to treatment with gefitinib

F Morgillo, WY Kim, ES Kim, F Ciardiello, WK Hong… - Clinical cancer …, 2007 - AACR
Lung cancer is the leading cause of cancer-related death in … lung tumor biology and
oncogenesis have provided several molecular targets for the treatment of non–small cell lung cancer

miR-138-5p reverses gefitinib resistance in non-small cell lung cancer cells via negatively regulating G protein-coupled receptor 124

Y Gao, XW Fan, WN Li, W Ping, Y Deng… - … and biophysical research …, 2014 - Elsevier
cell lung cancer (NSCLC) patients with EGFR activating mutations. However, therapeutic
effect is … We established a gefitinib-resistant cell model (PC9GR) by continually exposing PC9 …

[HTML][HTML] Environment impacts the metabolic dependencies of Ras-driven non-small cell lung cancer

SM Davidson, T Papagiannakopoulos, BA Olenchock… - Cell metabolism, 2016 - cell.com
lung cancers with isotope-labeled glucose or glutamine and compared the fate of these
nutrients in tumor … To examine metabolic differences between lung tumor and normal tissue, we …

[HTML][HTML] … -miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer cells

L Jiang, Q Huang, S Zhang, Q Zhang, J Chang, X Qiu… - BMC cancer, 2010 - Springer
… lower in NSCLC tissues than in adjacent normal lung tissues (LAC). Furthermore, the
results from the Spearman correlation test showed a negative relationship between hsa-miR-125a-…

[HTML][HTML] Human lung cancer cells express functionally active Toll-like receptor 9

D Droemann, D Albrecht, J Gerdes, AJ Ulmer… - Respiratory …, 2005 - Springer
… Three possibilities are conceivable: Either this could represent a bystander phenomenon,
a side effect of a pathway functional to a different purpose. Secondly the upregulation of TLR9 …

[HTML][HTML] … the efficacy of cisplatin by targeting cancer stem-like cells through p21 and cyclin D1-mediated tumour cell inhibition in non-small cell lung cancer cell lines

P Baharuddin, N Satar, KS Fakiruddin… - Oncology …, 2016 - spandidos-publications.com
… However the use of conventional drugs is limited due to the side effects and the resistant
phenotype acquired by tumours (58,59). Active compounds derived from plants, microbes and …

[HTML][HTML] Identification of uPAR-positive chemoresistant cells in small cell lung cancer

M Gutova, J Najbauer, A Gevorgyan, MZ Metz, Y Weng… - PloS one, 2007 - journals.plos.org
… Alternatively, uPAR-negative cancer cells may acquire uPAR expression under certain
culture conditions. Several uPAR-positive colonies have been picked and grown further for 2 …

Non–small cell lung cancer

DS Ettinger, W Akerley, G Bepler, MG Blum… - … comprehensive cancer …, 2010 - jnccn.org
… , thoracic surgery, and general lung cancer treatment to discuss the potential risks and …
is present in thyroid cancer tumors, whereas it is negative in lung cancer tumors. Pulmonary …

[HTML][HTML] … and the dietary flavonoid fisetin: a synergistic combination that induces mitotic catastrophe and autophagic cell death in A549 non-small cell lung cancer cells

A Klimaszewska-Wisniewska… - Cancer cell …, 2016 - Springer
… Nevertheless, the administration of this drug at optimum doses and for a prolonged time has
been hampered by the prevalence of serious side effects, such as neutropenia, neuropathy, …