Down-regulation of 14-3-3ζ suppresses anchorage-independent growth of lung cancer cells through anoikis activation

Z Li, J Zhao, Y Du, HR Park, SY Sun… - Proceedings of the …, 2008 - National Acad Sciences
… This study suggests a model in which anchorage-independent growth of lung cancer cells
… in lung cancer cells. Although Bad did not further increase with time upon cell detachment, …

Stimulation of the chemosensory TRPA1 cation channel by volatile toxic substances promotes cell survival of small cell lung cancer cells

EAM Schaefer, S Stohr, M Meister, A Aigner… - Biochemical …, 2013 - Elsevier
cell lung cancer (SCLC) cell lines. Of note, TRPA1 mRNA was also significantly higher
expressed in tumor … Four normal lung samples were negative for TRPA1 mRNA, eight normal …

miR-126 enhances the sensitivity of non-small cell lung cancer cells to anticancer agents by targeting vascular endothelial growth factor A

X Zhu, H Li, L Long, L Hui, H Chen… - Acta Biochim …, 2012 - academic.oup.com
… by pulmonary hemorrhage and toxic effects such as febrile … [41], so a new approach to evade
adverse effects of anti-VEGF … but also inhibits tumor cell growth and sensitizes tumor cells to …

Non-small-cell lung cancer

P Goldstraw, D Ball, JR Jett, T Le Chevalier, E Lim… - The Lancet, 2011 - thelancet.com
… In the decade since the last Lancet Seminar on lung cancer there have been advances in
many aspects of the classification, diagnosis, and treatment of non-small-cell lung cancer (…

MET as a possible target for non–small-cell lung cancer

AA Sadiq, R Salgia - Journal of clinical oncology, 2013 - ascopubs.org
… There is currently a randomized phase I/II trial looking at adverse effects of erlotinib with
or without the MET/VEGFR2 inhibitor foretinib. This trial is designed to investigate how well …

Small cell lung cancer

EB Bernhardt, SI Jalal - Lung cancer: Treatment and research, 2016 - Springer
… was again associated with increased rates of radiation-induced side effects including an
increased incidence of grade 3 esophagitis. The toxicity and the inconvenience of twice-daily …

… mechanisms for lung cancer risk of PM2.5: Induction of epithelial‐mesenchymal transition and cancer stem cell properties in human non‐small cell lung cancer cells

H Wei, F Liang, W Cheng, R Zhou, X Wu… - Environmental …, 2017 - Wiley Online Library
… Several potential mechanisms have been proposed to interpret the adverse lung effects
of PM 2.5 , including cytotoxicity induced by oxidative stress, oxidative DNA damage, …

[HTML][HTML] Curcumin inhibits cell proliferation and induces apoptosis of human non-small cell lung cancer cells through the upregulation of miR-192-5p and suppression …

H Jin, F Qiao, Y Wang, Y Xu… - Oncology …, 2015 - build.spandidos-publications.com
… , low toxicity and few side effects (9–13). However, the effect of curcumin on NSCLC and the
… In the present study, we examined the anticancer effect of curcumin on cell proliferation and …

[HTML][HTML] No erythropoietin-induced growth is observed in non-small cell lung cancer cells

A Frille, K Leithner, A Olschewski… - International …, 2017 - spandidos-publications.com
… , in tumor cells may be responsible for adverse effects and, … promotes tumor growth and
inhibits the death of cancer cells. … the implications of Epo upon the proliferation and survival of …

[HTML][HTML] Synergistic antitumor activity of oncolytic reovirus and chemotherapeutic agents in non-small cell lung cancer cells

S Sei, JK Mussio, Q Yang, K Nagashima… - Molecular cancer, 2009 - Springer
side effects [46, 47], corroborating that ReoT3D-taxane combination regimens can achieve
a … oncolytic effect in clinical settings and thus should be further explored as a novel treatment