Calcium sensing receptor exerts a negative regulatory action toward vasopressin-induced aquaporin-2 expression and trafficking in renal collecting duct

M Ranieri, A Di Mise, G Tamma, G Valenti - Vitamins and hormones, 2020 - Elsevier
… of the total abundance of the AQP2 protein in the cells. On the other … Ca 2 + in the renal
collecting duct attenuates short-term AVP-induced AQP2 trafficking through activation of the Ca 2

The ins and outs of aquaporin-2 trafficking

D Brown - American Journal of Physiology-Renal …, 2003 - journals.physiology.org
… by the expression of a dominant-negative form of the protein dynamin in LLC-PK 1 cells, …
Furthermore, earlier work demonstrated that Gα i-3 exerts a negative regulatory effect on the …

Aquaporin2 regulation in health and disease

M Judith Radin, MJ Yu, L Stoedkilde… - Veterinary clinical …, 2012 - Wiley Online Library
… Incubation of kidney slices with interleukin-1β decreases vasopressin binding,160 whereas
enhanced NF-κB signaling is a negative regulator of AQP2 gene expression.161 Inhibition of …

Negative feedback from CaSR signaling to aquaporin-2 sensitizes vasopressin to extracellular Ca2+

M Ranieri, G Tamma, A Di Mise, A Russo… - Journal of Cell …, 2015 - journals.biologists.com
… that CaSR expressed in distinct nephron segments exerts a negative feedback on … expression
of CaSR and the Ca 2+ -inhibitable AC6 could be responsible for the negative regulation

Minireview: aquaporin 2 trafficking

G Valenti, G Procino, G Tamma, M Carmosino… - …, 2005 - academic.oup.com
… that oocytes expressing wild-type, but not Ser-256-mutated, AQP2 responded … 2 mm) may
act as a negative regulator of V2 receptor signaling in the kidney. Calcium plays a role in AQP2

Repressive regulation of the aquaporin-2 gene

M Furuno, S Uchida, F Marumo… - American Journal of …, 1996 - journals.physiology.org
… strictly limited expression could be mediated by transcription … We first examined AQP2 mRNA
expression in many cultured … those exerting a negative effect on the target gene expression. …

Controlled aquaporin-2 expression in the hypertonic environment

U Hasler - American Journal of Physiology-Cell Physiology, 2009 - journals.physiology.org
AQP2 is an essential component of the urine concentration mechanism whose controlled
expression … This review focuses on changes of AQP2 abundance and trafficking in hypertonicity…

Vasopressin and the regulation of aquaporin-2

JLL Wilson, CA Miranda, MA Knepper - Clinical and experimental …, 2013 - Springer
… increased promoter activity, suggesting a negative regulatory role of GATA element. They …
to be associated with a defect in AQP2 trafficking, ie, short-term regulation of AQP2 [140]. In …

Aquaporin-2 localization in clathrin-coated pits: inhibition of endocytosis by dominant-negative dynamin

TX Sun, A Van Hoek, Y Huang… - American Journal …, 2002 - journals.physiology.org
… Furthermore, by using a fracture-label technique applied to LLC-PK 1 cells expressing an
AQP2-c-myc construct, we show that AQP2 is located in IMP aggregates and is concentrated in …

Long term regulation of aquaporin-2 expression in vasopressin-responsive renal collecting duct principal cells

U Hasler, D Mordasini, M Bens, M Bianchi… - Journal of Biological …, 2002 - ASBMB
… tRNA were used for hybridization with 2 × 10 5 cpm AQP2 probe and 5 × 10 4 cpm 18 S
rRNA probe. Yeast tRNA (25 μg) was used as a negative control. Hybridization was performed …