… Adenylate cyclase integrates positive and negative signals that act through G protein-coupled
cell-surface receptors with other extracellular stimuli to finely regulate levels of cAMP …

… Soluble guanylate cyclases (sGCs) function as heme … the basis for selective NO signaling
in aerobic cells. Using a … Fe-O bond 13 ; and (ii) negative polarity in the distal heme pocket as …

… This minireview highlights the studies which suggest that guanylate cyclase is a single-…
distinct signaling modules in a single membrane-spanning protein. A guanylate cyclase signaling …

… of the properties of cytosolic guanylate cyclase. Following the demonstration that hydroxylamine
and azide activate guanylate cyclase by catalase-dependent mechanisms (Mittal et al. …

… of the receptor guanylate cyclase family clearly indicate that the kinase homology domain
is required to transduce the ligand-binding signals and activate the guanylate cyclases ( …

… A soluble guanylate cyclase mediates negative signaling by ammonium on expression of
nitrate reductase in Chlamydomonas. Plant Cell 22: 1532–1548, 2010. Crossref, Medline, …

… Here, we characterized a novel component of the GC complex recently termed signaling …
by a guanylate cyclase complex conserved across the Apicomplexa. A signaling linked factor is …

… ) bind the transmembrane receptor guanylate cyclase C (GC-C)… guanylate cyclase (GC)
receptors and their peptide ligands regulate inflammation. For example, although GC-A signaling …

… Human guanylin is also known as guanylate cyclase activator 2A and is encoded by the
GUCA2A gene (1p35-p34). Its precursor protein, prepro-guanylin, contains 115 amino acid …

… gondii expresses a large guanylate cyclase (TgGC) protein, … can be bypassed by direct
activation of signaling by a Ca 2+ … that activates Ca 2+ signaling and motility in Toxoplasma. …