Efficacy of erlotinib as neoadjuvant regimen in EGFR-mutant locally advanced non-small cell lung cancer patients

L Xiong, Y Lou, H Bai, R Li, J Xia… - Journal of …, 2020 - journals.sagepub.com
… Our findings demonstrate that erlotinib is an effective neoadjuvant regimen in patients with
EGFR-mutant locally advanced NSCLC, paving the way for its extended use in neoadjuvant

[HTML][HTML] Erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 EGFR-mutant non-small-cell lung cancer: final overall survival analysis …

WZ Zhong, HH Yan, KN Chen, C Chen… - Signal transduction and …, 2023 - nature.com
… and safety of neoadjuvant and adjuvant targeted therapy with erlotinib compared with standard
… OS of neoadjuvant erlotinib was 42.2 months, which is a promising result for patients with …

Erlotinib Versus Gemcitabine Plus Cisplatin as Neoadjuvant Treatment of Stage IIIA-N2 EGFR-Mutant Non–Small-Cell Lung Cancer (EMERGING-CTONG 1103): A …

WZ Zhong, KN Chen, C Chen, CD Gu… - Journal of clinical …, 2019 - ascopubs.org
… analysis (one patient withdrew before treatment). The ORR for neoadjuvant erlotinib versus
GC … Three (9.7%) of 31 patients and zero of 23 patients in the erlotinib and GC chemotherapy …

A phase II trial of neoadjuvant erlotinib in patients with muscle‐invasive bladder cancer undergoing radical cystectomy: clinical and pathological results

RS Pruthi, M Nielsen, S Heathcote, EM Wallen… - BJU …, 2010 - Wiley Online Library
… maintenance erlotinib or observation, while patients with … the pT0 rate after neoadjuvant
erlotinib. Secondary endpoints … and tolerability of neoadjuvant erlotinib in patients with UC, and …

Concentrations of erlotinib in tumor tissue and plasma in non–small-cell lung cancer patients after neoadjuvant therapy

NAG Lankheet, EE Schaake, SA Burgers, R van Pel… - Clinical lung cancer, 2015 - Elsevier
… monotherapy in early stage NSCLC patients. The purpose of this study was to investigate
erlotinib plasma and lung tumor tissue concentrations after neoadjuvant erlotinib therapy. …

Erlotinib as Neoadjuvant Therapy in Stage IIIA (N2) EGFR Mutation‐Positive Non‐Small Cell Lung Cancer: A Prospective, Single‐Arm, Phase II Study

L Xiong, R Li, J Sun, Y Lou, W Zhang, H Bai… - The …, 2019 - academic.oup.com
… that neoadjuvant erlotinib improved the likelihood of surgery and was associated with a
good resection rate as shown by the high rate of prospective downstaging in patients with stage …

Is 18F-FDG PET/CT useful for the early prediction of histopathologic response to neoadjuvant erlotinib in patients with non–small cell lung cancer?

TS Aukema, I Kappers, RAV Olmos… - Journal of Nuclear …, 2010 - Soc Nuclear Med
… Currently, a Dutch multicenter phase II study of neoadjuvant erlotinib in operable patients
with … to neoadjuvant erlotinib early in the course of erlotinib therapy in patients with NSCLC. …

CTONG1103: Final overall survival analysis of the randomized phase 2 trial of erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 …

YL Wu, W Zhong, KN Chen, C Chen, F Yang, XN Yang… - 2021 - ascopubs.org
… Conclusion: Erlotinib as neoadjuvant/adjuvant therapy for resected N2 NSCLC was
feasibility and had a promising OS. The PFS survival advantage of E did not translate to OS …

[PDF][PDF] Tumor response and toxicity of neoadjuvant erlotinib in patients with early-stage non–small-cell lung cancer

EE Schaake, I Kappers, HE Codrington… - Journal of clinical …, 2012 - researchgate.net
… According to predefined criteria, neoadjuvant erlotinib has low toxicity and sufficient activity
… efficacy of a short course of preoperative erlotinib in patients with early-stage NSCLC who …

Pilot study of neoadjuvant treatment with erlotinib in nonmetastatic head and neck squamous cell carcinoma

F Thomas, P Rochaix, A Benlyazid, J Sarini… - Clinical Cancer …, 2007 - AACR
… In conclusion, the use of neoadjuvant erlotinib was well tolerated in patients with nonmetastatic
HNSCC. Further study is necessary to determine whether the encouraging antitumor …