Efficacy of erlotinib as neoadjuvant regimen in EGFR-mutant locally advanced non-small cell lung cancer patients

L Xiong, Y Lou, H Bai, R Li, J Xia… - Journal of …, 2020 - journals.sagepub.com
neoadjuvant regimen in patients with EGFR-mutantneoadjuvant therapy regimen based
on their EGFR status. Our study represents a foundation for the use of erlotinib in neoadjuvant

Neoadjuvant EGFR-TKI therapy for EGFR-mutant NSCLC: a systematic review and pooled analysis of five prospective clinical trials

L Sun, YJ Guo, J Song, YR Wang, SL Zhang… - Frontiers in …, 2021 - frontiersin.org
… of neoadjuvant EGFR-TKI for treatment of EGFR-mutant NSCLC… resectable EGFR-mutant
NSCLC treated with neoadjuvant … a more effective neoadjuvant targeted therapy regimen given …

Neoadjuvant Osimertinib With/Without Chemotherapy Versus Chemotherapy Alone for EGFR-Mutated Resectable Non-Small-Cell Lung Cancer: NeoADAURA

M Tsuboi, W Weder, C Escriu, C Blakely, J He… - Future …, 2021 - Taylor & Francis
… plasma samples for central EGFR mutation analysis will be … 1 day 1 of the neoadjuvant period,
the presurgical assessment (… cells (identified by routine hematoxylin and eosin staining) in …

[HTML][HTML] Osimertinib as neoadjuvant therapy in patients with EGFR-mutant resectable stage II-IIIB lung adenocarcinoma (NEOS): a multicenter, single-arm, open-label …

C Lv, W Fang, N Wu, W Jiao, S Xu, H Ma, J Wang… - Lung Cancer, 2023 - Elsevier
regimens in the neoadjuvant setting. The phase 2 ASCENT trial reported the results of
neoadjuvant afatinib in patients with stage III EGFR-mutant … Eight weeks of neoadjuvant afatinib …

Efficacy and safety of neoadjuvant targeted therapy vs. Neoadjuvant chemotherapy for stage iiia EGFR-mutant non-small cell lung cancer: A systematic review and …

D Chen, Z Jin, J Zhang, C Xu, K Zhu, Y Ruan… - Frontiers in …, 2021 - frontiersin.org
… field of stage IIIA epidermal growth factor receptor (EGFR) mutation-… and safety of neoadjuvant
targeted therapy (NTT) with neoadjuvant … setting, there is still controversy about the routine

Phase II study of biomarker-guided neoadjuvant treatment strategy for IIIA-N2 non-small cell lung cancer based on epidermal growth factor receptor mutation status

W Zhong, X Yang, H Yan, X Zhang, J Su… - Journal of Hematology & …, 2015 - Springer
… feasibility of biomarker-guided neoadjuvant therapy among patients with N2 NSCLC receiving
TKI or chemotherapy as neoadjuvant regimen based on EGFR mutation status. The RR …

Erlotinib Versus Gemcitabine Plus Cisplatin as Neoadjuvant Treatment of Stage IIIA-N2 EGFR-Mutant Non–Small-Cell Lung Cancer (EMERGING-CTONG 1103): A …

WZ Zhong, KN Chen, C Chen, CD Gu… - Journal of clinical …, 2019 - ascopubs.org
… plus cisplatin (GC chemotherapy) as neoadjuvant/adjuvant therapy in patients with …
EGFR mutations in exon 19 or 21 (EMERGING). Patients received erlotinib 150 mg/d (neoadjuvant

[HTML][HTML] Neoadjuvant and adjuvant epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy for lung cancer

H Zhai, W Zhong, X Yang, YL Wu - Translational lung cancer …, 2015 - ncbi.nlm.nih.gov
… that first-line EGFR-TKI regimen can improve tumor response … by different biological features
of EGFR mutant and wild type … and proof to validate efficacy of TKI neoadjuvant therapy. …

Epidermal growth factor receptor mutation and treatment outcome of mediastinoscopic N2 positive non-small cell lung cancer patients treated with neoadjuvant …

HK Ahn, YL Choi, JH Han, YC Ahn, K Kim, J Kim… - Lung Cancer, 2013 - Elsevier
… Thus, we analyzed the association between EGFR mutation and … received neoadjuvant CRT
followed by surgical resection. … The chemotherapy regimens consisted of weekly paclitaxel (…

[HTML][HTML] Does neoadjuvant targeted therapy provide an opportunity for resectable EGFR-mutant lung cancer: a real-world retrospective study

C Lv, Y Ma, Q Feng, F Lu, Y Chi, N Wu… - Journal of Thoracic …, 2020 - ncbi.nlm.nih.gov
… higher with neoadjuvant targeted therapy than with chemotherapy among patients harboring
EGFR mutation [objective response rate (ORR): 55.8% vs. 32.6%; P= 0.030]. EGFR exon 19 …