[HTML][HTML] Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach

CA Gadegbeku, DS Gipson, LB Holzman, AO Ojo… - Kidney international, 2013 - Elsevier
nephrotic syndrome. This includes a longitudinal observational cohort study, a pilot and
ancillary study … mechanistic disease classification for nephrotic syndrome and to identify clinical, …

Complete remission in the nephrotic syndrome study network

DS Gipson, JP Troost, RA Lafayette… - Clinical Journal of the …, 2016 - journals.lww.com
… This analysis from the Nephrotic Syndrome Study Network (NEPTUNE) assessed the
phenotypic and pathology characteristics of proteinuric patients undergoing kidney biopsy and …

Digital pathology evaluation in the multicenter Nephrotic Syndrome Study Network (NEPTUNE)

L Barisoni, CC Nast, JC Jennette… - Clinical Journal of the …, 2013 - journals.lww.com
… To improve this, the Nephrotic Syndrome Study Network (NEPTUNE) is systematically
applying digital pathology review in a multicenter study using renal biopsy whole slide imaging (…

[HTML][HTML] Single cell transcriptomics identifies focal segmental glomerulosclerosis remission endothelial biomarker

…, JB Hodgin, M Kretzler, KPM Project, NSS Network - JCI insight, 2020 - ncbi.nlm.nih.gov
… , the KPMP analyzes biopsy tissue in a multicenter research network to build cell-level
process maps of the kidney. This study aimed to establish a single cell RNA sequencing strategy …

Comparison of second-line immunosuppressants for childhood refractory nephrotic syndrome: a systematic review and network meta-analysis

HD Fu, GL Qian, Z Jiang - Journal of Investigative Medicine, 2017 - journals.sagepub.com
… In summary, our network meta-analysis found cyclophosphamide was the best second-…
nephrotic syndrome and tacrolimus was ranked as the second best. However, additional studies

… between patient-reported outcomes and clinical characteristics among patients with focal segmental glomerulosclerosis in the Nephrotic Syndrome Study Network

JP Troost, A Waldo, NE Carlozzi, S Murphy… - Clinical kidney …, 2020 - academic.oup.com
… Focal segmental glomerulosclerosis (FSGS) is a common cause of nephrotic syndrome, …
with nephrotic syndrome has suggested that the disease experience in nephrotic syndrome

Defining nephrotic syndrome from an integrative genomics perspective

MG Sampson, JB Hodgin, M Kretzler - Pediatric Nephrology, 2015 - Springer
… We will conclude by introducing a current implementation of this approach, the Nephrotic
Syndrome Study Network (NEPTUNE). We will describe how its design can uniquely aid in …

… glomerular disease among African-American children: a collaboration of the Chronic Kidney Disease in Children (CKiD) and Nephrotic Syndrome Study Network  …

DK Ng, CC Robertson, RP Woroniecki… - Nephrology Dialysis …, 2017 - academic.oup.com
… NEPTUNE is a prospective cohort study of individuals presenting with proteinuria (≥500
mg/24 h), with a suspected diagnosis of primary nephrotic syndrome [13]. Participants …

[HTML][HTML] Organoid single cell profiling identifies a transcriptional signature of glomerular disease

…, M Kretzler, ER cDNA Bank, NSS Network - JCI insight, 2019 - ncbi.nlm.nih.gov
Podocyte injury is central to many forms of kidney disease, but transcriptional signatures
reflecting podocyte injury and compensation mechanisms are challenging to analyze in vivo. …

[HTML][HTML] A new prospect for the treatment of nephrotic syndrome based on network pharmacology analysis

R Varghese, A Majumdar - Current Research in Physiology, 2022 - Elsevier
… and ER stress played a part in nephrotic syndrome and are critical pathways that need …
of nephrotic syndrome with the help of network pharmacology analysis. We identify network