… nervous system. The effective synaptic concentrations of glycine are regulated by glycine
transporters … and putative disease aspects of a small subfamily of these membrane proteins, the …

… of glycine transporters in both the CNS and the periphery suggests that the glycine transporter
… function by modulating glycine availability at the NMDA receptor-modulatory glycine site. …

… as a transmitter in the central nervous system (CNS). As an … Glycine transporters may
become major targets for therapeutic … of psychiatric diseases. Consequently, the potential of the …

… nervous system, glycine … Glycine transporter inhibitors may find application in the treatment
of muscle tone defects, epilepsy, schizophrenia, pain and neurodegenerative disorders. This …

… nervous system. GlyTs are members of the solute carrier family 6 (SLC6) and comprise glycine
transporter type … by a lesion or disorder in somatosensory nervous system, being not one …

… In the central nervous system, glycine may be either an … latter, glycine transporter-1 (GlyT1)
has a regulatory role for glycine … claimed for central and peripheral nervous system disorders. …

… the mammalian CNS (central nervous system). Glycinergic … disease aspects and putative
trafficking mechanisms of the mammalian transporter for the amino acid glycine: GlyT1 (glycine …

… to occur in the nervous system and glycine released from … the barrier imposed by glycine
transporters to the diffusion of … first neurological disease linked to mutations in a transporter for a …

… 1 is important only in the neonatal period, which may indicate that there is a possible adaptor
mechanism in the central nervous system that compensates for the glycine transporter 1 …

Intercellular communication in the central nervous system (CNS) 2 requires the precise
control of the duration and the intensity of neurotransmitter action at specific molecular targets. …