Topological analysis of the connectome of digital reconstructions of neural microcircuits

P Dotko, K Hess, R Levi, M Nolte, M Reimann… - arXiv preprint arXiv …, 2016 - arxiv.org
… activity in the microcircuit revealed novel … topological analysis of structural connectomics
and connectomics-based spatio-temporal activity in a biologically realistic neural microcircuit. …

Rich cell-type-specific network topology in neocortical microcircuitry

E Gal, M London, A Globerson, S Ramaswamy… - Nature …, 2017 - nature.com
… the effect of activity in the first neuron on the activity in the last neuron. It can be shown that
… that a spike in neuron i will initiate an extra (or abolished) spike in neuron j is proportional to …

Neuron geometry underlies universal network features in cortical microcircuits

E Gal, R Perin, H Markram, M London, I Segev - bioRxiv, 2020 - infoscience.epfl.ch
… asymmetrical morphology of neurons and their embedding in the cortical 3D space is indeed
sufficient to explain the preference for common motifs in a variety of neuronal microcircuits. …

[HTML][HTML] Computational Modelling and Topological Analysis of the striatal microcircuitry in health and Parkinson's disease

I Carannante - 2023 - diva-portal.org
… an in silico striatal microcircuit in health and PD, and to compare these two networks using
electrophysiological simulations and topological analysis. The neuron types included are the …

Differences in subcortico-cortical interactions identified from connectome and microcircuit models in autism

B Park, SJ Hong, SL Valk, C Paquola… - Nature …, 2021 - nature.com
… a broad microcircuit imbalance in autism that is not limited to a specific network. Our results
also indicate that these microcircuit … with prior resting-state fMRI analysis, and with the broad …

Data-driven modelling and topological analysis of the striatal microcircuitry in health and Parkinson's disease

I Carannante, JJ Hjorth, M Scolamiero… - ScienceOpen …, 2023 - scienceopen.com
… We apply topological methods to study the organization of the healthy and parkinsonian
networks and to compare them. We apply algebraic topology, in particular directed cliques (…

Dissecting functional connectivity of neuronal microcircuits: experimental and theoretical insights

S Feldt, P Bonifazi, R Cossart - Trends in neurosciences, 2011 - cell.com
… in neuronal networks. Therefore, in this review, we first introduce basic notions of network
topology and … how microcircuits are organized to produce function. Because different functional …

Scaling of topologically similar functional modules defines mouse primary auditory and somatosensory microcircuitry

AJ Sadovsky, JN MacLean - Journal of Neuroscience, 2013 - Soc Neuroscience
… This analysis revealed that the time course of neuronal recruitment was similar in both
regions of neocortex. In each circuit event, activity began in a small subset of neurons, quickly …

Towards a mathematical theory of cortical micro-circuits

D George, J Hawkins - PLoS computational biology, 2009 - journals.plos.org
… The networks can vary significantly in their topology, in how … onto cortical architecture and
microcircuits we must start with … as well as onto the microcircuits of cortical columns. However, …

Computational basis of neural elements

OE Arslan - Artificial Neural Network for Drug Design, Delivery and …, 2016 - Elsevier
… A number of microcircuit elements form complex network functions. To mediate cognition …
, multiple microcircuits join to form macrocircuits at multiple brain levels in the brain. Neuronal