Unraveling the mechanisms by which neural stem cells generate distinct cell types remains
a central challenge in central nervous system (CNS) biology. Recent studies have shown …

… energy metabolism regulate neural stem cell fate. The known … neural stem cells and their
differentiated progeny will also be discussed. A better understanding of how neural stem cells …

… powerhouse of the eukaryotic cell. Mitochondrial regulation of stem cell function has emerged
as a key mechanism that affects decisions pertaining to stem cell fate. Mitochondria are …

… neural stem cells … cell–signal–receptor trio and a local circuitry mechanism that control the
activation and self-renewal mode of quiescent adult neural stem cells in response to neuronal …

… can play a more active role in directing cell fate.Specifically, many studies have found evidence
of a role for Notch in promotingglial and perhaps stem cell identities. While intriguing, it is …

… Cell–cell contacts were less effective and the … neural characteristics was very small. We
propose that the selective promotion of neuronal and oligodendroglial fates in neural stem cell …

… To assess this default state, ES cells were placed in … ES cells were found to rapidly transition
directly into neural cells, … the default neural identity is that of a primitive neural stem cell (NSC…

… made up of primary progenitors known as neuroepithelial cells. By the onset of CNS
formation, neuroepithelial cells were thought be replaced by different neural stem cells (NSCs).…

… It develops from common multipotent neural stem cells (NSCs) that line the neural tube. …
all of these phases and give rise to specific neural cell types in a temporally defined and highly …

… a role in neural stem cell fate and maturation at virtually every stage of neural development.
BMP … Here, we elaborate the changing role of BMP signaling in neural stem cell fate and …