The role of p38 MAPK and its substrates in neuronal plasticity and neurodegenerative disease
SAL Corrêa, KL Eales - Journal of signal transduction, 2012 - Wiley Online Library
… of the p38 MAPK-MK2 and p38 MAPK-tau activation … neurodegenerative diseases. We will
also give some insight into how elucidating the precise role of p38 MAPK-MK2 and p38 MAPK-…
also give some insight into how elucidating the precise role of p38 MAPK-MK2 and p38 MAPK-…
[HTML][HTML] The p38 MAP kinase family as regulators of proinflammatory cytokine production in degenerative diseases of the CNS
AD Bachstetter, LJ Van Eldik - Aging and disease, 2010 - ncbi.nlm.nih.gov
… to present an overview of the p38 MAPK family as it relates to … p38 MAPK family that
emphasizes the role of individual p38 … in brain injury and neurodegenerative disease, and there …
emphasizes the role of individual p38 … in brain injury and neurodegenerative disease, and there …
The p38 MAP kinase signaling pathway in Alzheimer's disease
GVW Johnson, CDC Bailey - Experimental neurology, 2003 - Elsevier
… neurodegeneration in AD likely is the reason there are no effective treatments to prevent the
onset and/or progression of the disease. … activate members of the p38 MAP kinase family 19, …
onset and/or progression of the disease. … activate members of the p38 MAP kinase family 19, …
MAPKs: new targets for neurodegeneration
SJ Harper, N Wilkie - Expert opinion on therapeutic targets, 2003 - Taylor & Francis
… (JNKs) and the p38 MAPKs. The evidence for activation of each of these pathways in …
MAPK enzymes in neurodegenerative diseases, and postulate on the possible roles of MAPK …
MAPK enzymes in neurodegenerative diseases, and postulate on the possible roles of MAPK …
Compromised MAPK signaling in human diseases: an update
EK Kim, EJ Choi - Archives of toxicology, 2015 - Springer
… disorders such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral
sclerosis. The JNK and p38 MAPK signaling … MAPK signaling in neurodegenerative diseases …
sclerosis. The JNK and p38 MAPK signaling … MAPK signaling in neurodegenerative diseases …
… c-JNK/p38MAPK signaling overactivation involved in the progression of multiple sclerosis: possible therapeutic targets and impact on neurodegenerative diseases
A Singh, S Upadhayay, S Mehan - Neurotoxicity research, 2021 - Springer
… As mentioned earlier, p38 MAPK was identified in an inflammatory response for its role in
controlling the gene expression of pro-inflammatory cytokines, specifically IL-1 and TNF-, in …
controlling the gene expression of pro-inflammatory cytokines, specifically IL-1 and TNF-, in …
Targeting p38 MAPK pathway for the treatment of Alzheimer's disease
L Munoz, AJ Ammit - Neuropharmacology, 2010 - Elsevier
… on the role of p38 MAPK in neurodegeneration, with a focus on Alzheimer's disease, by …
our understanding of this neurodegenerative disease, it still remains an incurable disorder. …
our understanding of this neurodegenerative disease, it still remains an incurable disorder. …
Recent advances in the inhibition of p38 MAPK as a potential strategy for the treatment of Alzheimer's disease
… P38 MAPK inhibitors have recently been claimed as novel and potential therapeutics for
neurodegenerative diseases… the roles of p38 MAPK in neurodegenerative disease, detailed …
neurodegenerative diseases… the roles of p38 MAPK in neurodegenerative disease, detailed …
Involvement of p38 MAPK in synaptic function and dysfunction
C Falcicchia, F Tozzi, O Arancio, DM Watterson… - International journal of …, 2020 - mdpi.com
… of p38 MAPK in the regulation of synaptic plasticity and its implication in an animal model of
neurodegeneration. In … glial cell activation is present in neurodegenerative diseases [2]. The …
neurodegeneration. In … glial cell activation is present in neurodegenerative diseases [2]. The …
When good kinases go rogue: GSK3, p38 MAPK and CDKs as therapeutic targets for Alzheimer's and Huntington's disease
SR D'Mello - International Journal of Molecular Sciences, 2021 - mdpi.com
… play a key role in the pathogenesis of both AD and HD as well as several other
neurodegenerative diseases. Prominent among these kinases are glycogen synthase kinase …
neurodegenerative diseases. Prominent among these kinases are glycogen synthase kinase …
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