RNA editing in neurological and neurodegenerative disorders

PH Costa Cruz, Y Kawahara - RNA Editing: Methods and Protocols, 2021 - Springer
… vulnerable to dysregulation of A-to-I RNA editing. Here, we focus on how aberrant A-to-I
RNA editing is involved in neurological and neurodegenerative diseases of humans including …

[HTML][HTML] Contribution of A-to-I RNA editing, M6A RNA Methylation, and Alternative Splicing to physiological brain aging and neurodegenerative diseases

V Tassinari, P La Rosa, E Guida, A Colopi… - Mechanisms of ageing …, 2023 - Elsevier
A-to-I RNA editing process and its contribution to neurodegenerative diseases. Schematic
representation showing A-to-I RNA editing process and its implications in Amyotrophic lateral …

Genetic control of RNA editing in neurodegenerative disease

S Wu, Q Xue, M Yang, Y Wang, P Kim… - Briefings in …, 2023 - academic.oup.com
… or regulations, potentially involving in neurodegenerative pathogenesis. Its variabilities are
… of neurodegenerative disease-susceptibility variants from the view of A-to-I RNA editing, we …

A systematic review of common and brain-disease-specific RNA editing alterations providing novel insights into neurological and neurodegenerative disease …

K Karagianni, S Pettas, G Christoforidou, E Kanata… - Biomolecules, 2022 - mdpi.com
… events were reported in different organisms, and corresponding databases (RADAR,
rigorously annotated database of A-to-I RNA editing [67], DARNED [68], and REDIportal [69] have …

Dysregulated A to I RNA editing and non-coding RNAs in neurodegeneration

M Singh - Frontiers in genetics, 2013 - frontiersin.org
… , in neurodegenerative diseases. These ncRNA species are ripe for research to analyze
whether RNA editing … Furthermore, the fact that binding of ADARs in the absence of editing also …

The Potential Regulation of A-to-I RNA editing on Genes in Parkinson's Disease

S Wu, Q Xue, X Qin, X Wu, P Kim, J Chyr, X Zhou… - Genes, 2023 - mdpi.com
… us understand neurodegenerative pathogenesis. In this study, we identified 9897 A-to-I RNA
editing … in the pathogenesis of neurological and neurodegenerative disorders. For example, …

A-to-I RNA editing and human disease

S Maas, Y Kawahara, KM Tamburro, K Nishikura - RNA biology, 2006 - Taylor & Francis
… proteins in axons of motor neurons is observed, but as for other types of protein deposits
associated with several neurodegenerative diseases (such as Alzheimer’s and Parkinson …

RNA editing: a new therapeutic target in amyotrophic lateral sclerosis and other neurological diseases

T Hosaka, H Tsuji, S Kwak - International Journal of Molecular Sciences, 2021 - mdpi.com
… the failure of A-to-I RNA editing in neurological diseases. Moreover, as … of RNA editing with
neurodegenerative diseases or current and promising gene therapies for neurodegeneration

Differential analysis of A-to-I mRNA edited sites in Parkinson's disease

DV Pozdyshev, AA Zharikova, MV Medvedeva… - Genes, 2021 - mdpi.com
… of differences in A-to-I RNA editing levels and specificity of mRNA editing sites in brain …
reported evaluations of RNA editing levels in other neurodegenerative diseases. Increased …

RNA editing deficiency in neurodegeneration

I Lorenzini, S Moore, R Sattler - … in Neurodegenerative Diseases, 2018 - Springer
RNA editing deficits for chronic and acute neurodegenerative disorders, neuropsychiatric
diseases… miRNAs can undergo A-to-I RNA editing at premature states when the miRNA has a …