Role of oxidative stress and antioxidants in neurodegenerative diseases

AV Rao, B Balachandran - Nutritional neuroscience, 2002 - Taylor & Francis
neurodegenerative disorders with emphasis on genetic origin and its correlation with oxidative
stress of neurodegenerative disordersstrategy is to utilize lycopene, a potent antioxidant

Prospective function of different antioxidant containing natural products in the treatment of neurodegenerative diseases

MH Rahman, R Akter, MA Kamal - … & Neurological Disorders …, 2021 - ingentaconnect.com
… of neurodegenerative disorders. Moreover, most NPs comprise phytoconstituents, including
polyphenolic antioxidants; … , profiling strategies, computational biology strategies, large data, …

Nanotechnology and antioxidant therapy: an emerging approach for neurodegenerative diseases

C Fernandes, C Oliveira, S Benfeito… - Current medicinal …, 2014 - ingentaconnect.com
… the initiating factors that trigger many neurodegenerative disorders, to date, no novel …
antioxidants or the intake of exogenous dietary antioxidants can be an effective therapeutic strategy

A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes

E Esposito, D Rotilio, V Di Matteo, C Di Giulio… - Neurobiology of …, 2002 - Elsevier
… nutritional antioxidants can reduce or block neuronal death occurring in neurodegenerative
disorders … of neurodegenerative disorders, such as AD, PD, and ALS. The effects of ROS and …

Oxidative stress in neurodegenerative diseases

E Niedzielska, I Smaga, M Gawlik, A Moniczewski… - Molecular …, 2016 - Springer
… in the pathogenesis of neurodegenerative disorders. Clinical … and by lower levels of antioxidant
defense biomarkers in the … we explore pharmacotherapeutic strategies for OS reduction. …

Common protective strategies in neurodegenerative disease: focusing on risk factors to target the cellular redox system

P Hrelia, G Sita, M Ziche, E Ristori… - Oxidative Medicine …, 2020 - Wiley Online Library
… targetable, and the only strategy tested so far, using antioxidants, was unsuccessful or even
… in the quest for new preventive pharmacological strategies to neurodegenerative disorders. …

Potential therapeutic strategies of phytochemicals in neurodegenerative disorders

DK Yadav - Current topics in medicinal chemistry, 2021 - ingentaconnect.com
… The pathology of neurodegenerative disorders is based on oxidative stress (OS). High
concentrations of reactive oxygen species (ROS) production and reduced activation of antioxidant

Multiple antioxidants in the prevention and treatment of neurodegenerative disease: analysis of biologic rationale

KN Prasad, WC Cole, AR Hovland… - Current opinion in …, 1999 - journals.lww.com
strategies are available. The analysis of existing literature suggests that oxidative stress
is a major risk factor for these neurodegenerative … with many neurodegenerative disorders, …

Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of vitagenes

V Calabrese, E Guagliano, M Sapienza… - Neurochemical …, 2007 - Springer
… Reduced expression and/or activity of antioxidant proteins lead to oxidative stress, accelerated
aging and neurodegeneration. However, while excess reactive oxygen species (ROS) …

[PDF][PDF] Potential of redox therapies in neurodegenerative disorders

E Miller, L Markiewicz, J Kabzinski, D Odrobina… - Front Biosci, 2017 - researchgate.net
… stress is currently one of the main neuroprotective strategies. The World … of antioxidant
genes have been proposed as therapeutic candidates, eg, for neurodegenerative disorders NRF2 …