Looking backward to move forward: early detection of neurodegenerative disorders

ST DeKosky, K Marek - Science, 2003 - science.org
… of and potential therapy for neurodegenerative disorders. These diseases, including …
Huntington's disease (HD), and other neurodegenerative dementias, generally begin late in life and …

Staging neurodegenerative disorders: structural, regional, biomarker, and functional progressions

T Archer, RM Kostrzewa, RJ Beninger, T Palomo - Neurotoxicity research, 2011 - Springer
… The notion of staging in the neurodegenerative disorders is modulated by the constant
and progressive loss of several aspects of brain structural integrity, circuitry, and neuronal …

Biomarkers of neurodegenerative disorders: how good are they?

V Rachakonda, TH Pan, WD Le - Cell Research, 2004 - nature.com
… And lastly, the marker specificity should be high enough to distinguish AD from other
neurodegenerative disorders. Based on these criteria, scientists have been able to eliminate many …

Neurodegenerative disorders

L Wang, JR Petrella - Functional Neuroimaging, 2019 - taylorfrancis.com
… fully developed in the middle or late stage of disease. However, potential … early stage of
neural degeneration before functional decline occurs. Thus, biomarkers for neurodegenerative

The potential for natural antioxidant supplementation in the early stages of neurodegenerative disorders

F Oppedisano, J Maiuolo, M Gliozzi… - International journal of …, 2020 - mdpi.com
… the early phases of neurodegenerative diseases. The present review will deal with the
pathophysiological mechanisms underlying the early stages of the neurodegenerative process. In …

Neuroregeneration in neurodegenerative disorders

AM Enciu, MI Nicolescu, CG Manole, DF Mureşanu… - BMC neurology, 2011 - Springer
… However, we hypothesize that the brain possesses, at least in early and medium stages of
disease, a "neuroregenerative reserve", that could be exploited by growth factors or stem cells-…

Molecular diagnostics of neurodegenerative disorders

M Agrawal, A Biswas - Frontiers in molecular biosciences, 2015 - frontiersin.org
neurodegenerative disorderearly detection and effective treatment of neurodegeneration.
In this short review, we focus on recent advances made in major neurodegenerative disorders

Social inappropriateness in neurodegenerative disorders

P Desmarais, KL Lanctôt, M Masellis… - International …, 2018 - cambridge.org
… in prodromal stages of neurodegenerative disorders, by … and impairment in different
neurocognitive disorders. We will also … regularly observed in neurodegenerative disorders and …

Disease modification and Neuroprotection in neurodegenerative disorders

J Cummings - Translational Neurodegeneration, 2017 - Springer
… Alzheimer’s disease (AD) and many other neurodegenerative disorders (NDD) are … NDD
are protein aggregation disorders with neurodegeneration [5]. Neurodegeneration is defined as …

Sleep and quantitative EEG in neurodegenerative disorders

D Petit, JF Gagnon, ML Fantini, L Ferini-Strambi… - Journal of …, 2004 - Elsevier
… AD is a progressive neurodegenerative disorder characterized by progressive memory
decline, impairment of spatial and temporal orientation and progressive aphasia and apraxia. It is …