Impairments in dendrite morphogenesis as etiology for neurodevelopmental disorders and implications for therapeutic treatments
T Copf - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
… neurodevelopmental disorders, with focus on autism and schizophrenia. We next discuss
high-risk genes for these disorders and their role in dendrite morphogenesis. … relate to dendrite …
high-risk genes for these disorders and their role in dendrite morphogenesis. … relate to dendrite …
Plasticity of dendritic spines: Molecular function and dysfunction in neurodevelopmental disorders
J Nishiyama - Psychiatry and clinical neurosciences, 2019 - Wiley Online Library
… in dendritic spine shape, size, and density have been implicated in many neurodevelopmental
disorders… (ID), suggesting that dendritic spine dysfunction is a common pathomechanism. …
disorders… (ID), suggesting that dendritic spine dysfunction is a common pathomechanism. …
Dendrite and spine modifications in autism and related neurodevelopmental disorders in patients and animal models
V Martínez‐Cerdeño - Developmental neurobiology, 2017 - Wiley Online Library
… FMRP has been shown to interact in vitro with p21-activated kinases (PAK), an enzyme
known to play a critical role in actin polymerization and dendritic spine morphogenesis. The …
known to play a critical role in actin polymerization and dendritic spine morphogenesis. The …
… of dendritic spine development and plasticity by BDNF and vesicular trafficking: fundamental roles in neurodevelopmental disorders associated with mental …
CA Chapleau, JL Larimore, A Theibert… - … of neurodevelopmental …, 2009 - Springer
… of axonal and dendritic differentiation, and in dendritic spine morphogenesis. Several genes
that are either mutated or deregulated in neurodevelopmental disorders associated with …
that are either mutated or deregulated in neurodevelopmental disorders associated with …
The dendritic tree and brain disorders
VA Kulkarni, BL Firestein - Molecular and Cellular Neuroscience, 2012 - Elsevier
… Dendrite morphogenesis is a complex but well-orchestrated process and includes the
development of dendritic branches, forming characteristic dendrite … neurodevelopmental disorders, …
development of dendritic branches, forming characteristic dendrite … neurodevelopmental disorders, …
Molecular mechanisms of dendrite morphogenesis
J Arikkath - Frontiers in cellular neuroscience, 2012 - frontiersin.org
… that regulate dendrite morphogenesis, particularly in cortical … of aberrant dendritic morphology
for human disease. Finally, we … for neurodevelopmental disorders and acute neurological …
for human disease. Finally, we … for neurodevelopmental disorders and acute neurological …
Regulation of dendrite morphogenesis by extrinsic cues
… of dendrite development. We also highlight how extrinsic cues influence local and global
intracellular mechanisms of dendrite morphogenesis. Finally, … of neurodevelopmental disorders. …
intracellular mechanisms of dendrite morphogenesis. Finally, … of neurodevelopmental disorders. …
Cadherins and catenins in dendrite and synapse morphogenesis
E Seong, L Yuan, J Arikkath - Cell adhesion & migration, 2015 - Taylor & Francis
… been implicated in a variety of neurodevelopmental disorders. In this review, we … of dendrite
and synapse architecture and function and their relevance to human neurological disorders. …
and synapse architecture and function and their relevance to human neurological disorders. …
Molecular mechanisms that mediate dendrite morphogenesis
JL Lefebvre - Current topics in developmental biology, 2021 - Elsevier
… and are implicated in neurodevelopmental disorders. In this … of dendritic morphologies is
produced in nervous systems. In this chapter, I review mechanisms of dendrite morphogenesis …
produced in nervous systems. In this chapter, I review mechanisms of dendrite morphogenesis …
Current best practices for analysis of dendritic spine morphology and number in neurodevelopmental disorder research
… Indeed, while this Perspective focuses on neurodevelopmental disorders, dendritic spine …
neurodegenerative disorders such as Alzheimer’s disease and dementia, (31,32) Huntington’s …
neurodegenerative disorders such as Alzheimer’s disease and dementia, (31,32) Huntington’s …
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