… more tumors associated with the MEN 1 syndrome, as well as … tumor syndromes that are
atypical, yet suggestive of MEN 1. … MEN 1 tumors and tumors rarely associated with MEN 1; (2) a …

… The most frequent one is the MEN1 syndrome, which is characterized by primary
hyperparathyroidism (PHPT) due to parathyroid hyperplasia/adenomas, functional or non-functional …

… every patient affected with a neuroendocrine thymic neoplasm for MEN1 syndrome. … We
also recommend screening every patient diagnosed with a thymic neoplasm for MEN1 syndrome…

… dominant genetic basis of the disease recognized. This condition was later termed the
Wermer syndrome or multiple endocrine adenomatosis, but MEN1 is now the preferred term. …

… nuclear factors, are generally associated with loss of function mutations in the aetiology of
family cancer syndromes (23,24) and LOH studies of MEN1 tumours have indicated that the …

… ) is a classic hereditary tumor syndrome characterized by a … neuroendocrine neoplasias
and hormone excess syndromes. The disease is caused by inactivating mutations of the MEN1 …

… of the disease, the encoded protein (MENIN) and its role in the development of sporadic
neuroendocrine and other neoplasms … of the MEN1 syndrome, alterations of the MEN1 gene in …

… tumors (pNETs) are frequent in multiple endocrine neoplasia type 1 (MEN1) syndrome. They
are usually not surgically treated unless larger than 1 to 2 cm or a growth rate > 0.5 cm per …

… in patients with MEN1 syndrome [1–4]. However, whether these ependymomas represent …
neoplasms or arose as part of MEN1 or an alternative multiple endocrine neoplasia syndrome …

… Most of the carcinoid tumors in MEN1 syndrome originate in the foregut and occur in 10% of
the cases. These tumors rarely secrete adrenocorticotropic hormone (ACTH), calcitonin, and …