Blockage of the neurokinin 1 receptor and capsaicin-induced ablation of the enteric afferent nerves protect SCID mice against T-cell-induced chronic colitis
M Gad, A Elm Pedersen, N Ny Kristensen… - Inflammatory bowel …, 2009 - academic.oup.com
… NK-1 receptors and elimination of afferent nociceptive nerves inhibit the development of chronic
colitis. Thus, our data might suggest new treatment … Ki = 0.31 nM), 19 suggesting that the …
colitis. Thus, our data might suggest new treatment … Ki = 0.31 nM), 19 suggesting that the …
[HTML][HTML] Cytokine storm in COVID-19: the current evidence and treatment strategies
Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen - Frontiers in immunology, 2020 - frontiersin.org
… suggest treating the cytokine storm in COVID-19 should base on the laboratory results of
cytokines and chemokines. Meanwhile, adjusting the parameters of the devices (eg, treatment …
cytokines and chemokines. Meanwhile, adjusting the parameters of the devices (eg, treatment …
[HTML][HTML] Confronting COVID-19-associated cough and the post-COVID syndrome: role of viral neurotropism, neuroinflammation, and neuroimmune responses
… Evidence-based treatment options for COVID-19 cough are needed because patients with
cough caused by common viral infections, including cold and flu, frequently resort to over-the-…
cough caused by common viral infections, including cold and flu, frequently resort to over-the-…
Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions
… In this review, we will not discuss antiviral strategies used to treat COVID-19, nor will we
discuss how to manage the wide spectrum of SARS-CoV2 infection-related complications, such …
discuss how to manage the wide spectrum of SARS-CoV2 infection-related complications, such …
COVID‐19, nausea, and vomiting
PLR Andrews, W Cai, JA Rudd… - … of gastroenterology and …, 2021 - Wiley Online Library
… treatments (eg 5-HT 3 and NK 1 receptor antagonists). Further studies of mechanisms are
needed and in addition to in vitro studies of EEC cell lines these may include studies in the …
needed and in addition to in vitro studies of EEC cell lines these may include studies in the …
Truncated neurokinin-1 receptor is increased in colonic epithelial cells from patients with colitis-associated cancer
E Gillespie, SE Leeman, LA Watts… - Proceedings of the …, 2011 - National Acad Sciences
… (CAC) suggesting that NK-1R may play a functional role in the disease; treatment with an …
The science around the use of masks by the public to impede COVID-19 transmission is …
The science around the use of masks by the public to impede COVID-19 transmission is …
[HTML][HTML] COVID-19: immunopathogenesis and Immunotherapeutics
L Yang, S Liu, J Liu, Z Zhang, X Wan… - … and targeted therapy, 2020 - nature.com
… tumor effects of NK cell-based immunotherapy, 63 where NK cells … For COVID-19 treatment,
NK cell-based therapy has been … LabCell to develop NK cell combination therapy and rapidly …
NK cell-based therapy has been … LabCell to develop NK cell combination therapy and rapidly …
[HTML][HTML] Novel coronavirus-induced NLRP3 inflammasome activation: a potential drug target in the treatment of COVID-19
A Shah - Frontiers in immunology, 2020 - frontiersin.org
… target in the treatment of coronavirus disease 2019 (COVID-19), … effects in the treatment of
SARS-CoV-2 (COVID-19). … severe and acute respiratory syndrome coronavirus (SARS-CoV) …
SARS-CoV-2 (COVID-19). … severe and acute respiratory syndrome coronavirus (SARS-CoV) …
[PDF][PDF] On the role of “substance P” in the respiratory tract in corona infections to the causes of corona-related brain destruction
R Mehboob, P Oehme, G Pfaff - Leibniz Online, 2023 - leibnizsozietaet.de
… belongs to the group of neurokinins, the COVID-19 infection, and air … These effects are
independent of the NK 1 receptor. … , for the therapy of severe COVID courses. Mehboob proposed …
independent of the NK 1 receptor. … , for the therapy of severe COVID courses. Mehboob proposed …
[HTML][HTML] Flattening the COVID-19 curve with natural killer cell based immunotherapies
M Market, L Angka, AB Martel, D Bastin… - Frontiers in …, 2020 - frontiersin.org
… NK cells respond in both early and late coronavirus infections, and the implication for ongoing
… modulating treatment options that are being developed for the current COVID-19 crisis. …
… modulating treatment options that are being developed for the current COVID-19 crisis. …