… tachykinin NK2 receptor antagonist MEN11420 (nepadutant) was found to inhibit
bronchoconstriction induced by inhaled neurokinin … the nonpeptide tachykinin NK2 receptor …

… tachykinin NK2 receptor antagonist SR 48968 inhibits NKA-induced bronchoconstriction in
patients with asthma. … -induced bronchoconstriction in asthma is mediated via activation of the …

… report indicate that DNK333 blocks neurokinin A‐induced bronchoconstriction in patients with
asthma. … In this study the dual tachykinin NK 1 /NK 2 receptor antagonist DNK333 inhibited …

… tachykinin receptor in various animal models (17-19, 23). The reported affinity of the antagonist
for the receptor … guinea pig ileum and 7.50 for neurokinin A-induced contraction of rat vas …

… Tachykinins substance P, neurokinin A and neurokinin B seem to account for … In addition,
contrasting the effects of NK1 and NK2 receptor activation in the airways, which induce …

… to determine whether neurokinin B (NKB) or specific agonists of tachykinin NK 3 receptors,
[… Bronchoconstriction induced by tachykinins administered by aerosol was also determined. …

… Neurokinin A-induced bronchospasm in subjects with asthma can be prevented by the …
Recent findings indicate that inhaled neurokinin Ainduced bronchoconstriction in humans can be …

… tachykinins to respiratory symptoms of asthma can only be evaluated practically in humans
using tachykinin receptor … 48,968 of neurokinin A-induced dyspnea was due to NK 2 receptor …

… The tachykinins substance P and neurokinin A are contained … role of tachykinins and their
receptors in asthma and chronic … tachykinin receptor antagonists in animal models of asthma …

… , whilst tachykinin NK1 and tachykinin NK2 receptors are express… changes in neurokinin
receptor expression in asthma. There … Neurokinin A-induced bronchial hyperresponsiveness to …