… the astrocytic water channel aquaporin-4 (AQP4). Immunological … distinguishing CNS AQP4
autoimmunity from classical … but neurological signs in the initial attack of AQP4 autoimmunity …

… Neuromyelitis optica (NMO) is an inflammatory autoimmune neurologic disease that typically
presents as recurrent longitudinally extensive transverse myelitis and optic neuritis. The …

… with the evolving nomenclature used in autoimmune neurological diseases that is molecular
target defined. The term autoimmune AQP4 channelopathy is inclusive of the expanding …

… Recently, the demonstration of a pathogenic role for the anti-aquaporin 4 (AQP4) antibody
… with CNS AQP4 autoimmunity. Twelve patients had Sjögren syndrome, and 4 patients had …

… neurologic, serologic, and radiographic findings associated with CNS AQP4 autoimmunity in
… We propose that CNS AQP4 autoimmunity in children is a distinct biomarker-defined entity. …

… center for AQP4-IgG evaluation in the United States. The aim of this study is to determine the
sex and age distribution of AQP4 autoimmunity using data derived from AQP4-IgG testing in …

… The data we present suggest that aquaporin-4 autoimmunity may, in some patients, reflect
a tumor-initiated immune response. We report clinical and oncologic associations for 28 of 31 …

… diagnosed prior to 2004 (when AQP4-IgG was discovered) … in a care facility without
subsequent neurological follow-up. In … and seroincidence of AQP4-IgG autoimmunity and NMO/…

… Paraneoplastic autoimmune neurological disorders are a remote manifestation of a patient's
immune response initiated by onconeural antigens expressed in a cancer that is often occult…

… in AQP4 has increased due to the discovery that it is the target antigen in the neurological
autoimmune … NMOSD is an autoimmune astrocytophathy commonly characterized by astrocyte …