Intracerebral hemorrhage-induced neuronal death

C Gong, N Boulis, J Qian, DE Turner, JT Hoff… - Neurosurgery, 2001 - journals.lww.com
… The mechanisms underlying neural injury in intracerebral hemorrhage (ICH) remain uncertain.
The present two-part study investigated cell death in the region of ICH and its association …

Cell death in experimental intracerebral hemorrhage: the “black hole” model of hemorrhagic damage

RA Felberg, JC Grotta, AL Shirzadi… - Annals of Neurology …, 2002 - Wiley Online Library
… The decreased neuronal density in the “transition zone” may also be explained by factors
other than apoptotic neuronal death. One possibility is the coexistence of edema. Increased …

Glial responses, neuron death and lesion resolution after intracerebral hemorrhage in young vs. aged rats

JK Wasserman, H Yang… - European Journal of …, 2008 - Wiley Online Library
Intracerebral hemorrhage (ICH) usually affects older humans … , neuron death and lesion
resolution after a hemorrhage in … volume and number of dying neurons at 1 and 3 days, and the …

Neuron death and inflammation in a rat model of intracerebral hemorrhage: effects of delayed minocycline treatment

JK Wasserman, LC Schlichter - Brain research, 2007 - Elsevier
… Because inflammation has been associated with neuron death in models of stroke and other
types of brain injury, we investigated the spatial–temporal relationship between neuron loss …

Ferroptosis, a regulated neuronal cell death type after intracerebral hemorrhage

Q Bai, J Liu, G Wang - Frontiers in Cellular Neuroscience, 2020 - frontiersin.org
neurons. Therefore, ferroptosis is becoming a common trend in research of neuronal death
… Accumulative data suggest that the inhibition of ferroptosis may effectively prevent neuronal

Ultrastructural characteristics of neuronal death and white matter injury in mouse brain tissues after intracerebral hemorrhage: coexistence of ferroptosis, autophagy …

Q Li, A Weiland, X Chen, X Lan, X Han… - Frontiers in …, 2018 - frontiersin.org
… the ultrastructure of neural soma, axons, synapses, myelination, and innate immune cells
using TEM during the acute and chronic phases of ICH. We hypothesized that neuronal death, …

Programmed cell death after intracerebral hemorrhage

T Bobinger, P Burkardt, HB Huttner… - Current …, 2018 - ingentaconnect.com
neurons was observed, indicating that apoptosis significantly contributed to the neuronal death
… Autophagic inhibition in the microglia resulted in a significant decrease in neuronal death

A new hippocampal model for examining intracerebral hemorrhage-related neuronal death: effects of deferoxamine on hemoglobin-induced neuronal death

S Song, Y Hua, RF Keep, JT Hoff, G Xi - Stroke, 2007 - Am Heart Assoc
… of intracerebral hemorrhage-induced neuronal deathneuronal death measurements.
Results— Compared with saline, hemoglobin or iron injection caused hippocampal neuronal death

Modes of brain cell death following intracerebral hemorrhage

Y Zhang, S Khan, Y Liu, R Zhang, H Li, G Wu… - Frontiers in Cellular …, 2022 - frontiersin.org
… It can form highly toxic hydroxyl radicals to attack DNA, proteins, and lipid membranes,
thereby disrupting cellular functions and causing neuronal death. Iron is required for the …

Deferoxamine reduces neuronal death and hematoma lysis after intracerebral hemorrhage in aged rats

T Hatakeyama, M Okauchi, Y Hua, RF Keep… - Translational stroke …, 2013 - Springer
… acute ICH-induced neuronal death and whether it affects the … Rats were euthanized 1, 3, or
7 days later for neuronal death … In conclusion, DFX reduces neuronal death and neurological …